日度归档：2020年12月29日

harlan teklad官网动物饲料代理商 强力霉素 多西环素 TD.01306 TD.05125 Doxycycline diets

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harlan teklad官网动物饲料代理商 强力霉素 多西环素 TD.01306 TD.05125

多西环素饮食

EnvigoTeclad饮食使各种多西环素包含饮食为您的Tet调节系统。可以添加一系列的多西环素(如强力霉素)。典型的包含率是200毫克/千克和625毫克/千克，但一些研究人员指定一个更高或更低的水平。

饮食是很容易定制的，因为他们是新鲜的，当订购。我们目前有超过150个不同的强力霉素配方组合。我们可能有一个现有的产品编号，以满足您的规格。规格包括：基础饮食，多西环素浓度和食用色素。联系我们如果你在下面找不到合适的选择的话，来讨论你的需求。

全球饮食基础
产品编号 基础饮食 强力霉素透明
每公斤饲料毫克		 每日强力霉素
3-5克日粮中的毫克		 替代
食用色素
TD.01306
备好		 2018 625 1.6 – 2.7 TD.08541红色
TD.120769蓝色
TD.00502 2018 200 0.5 – 0.9 TD.04104绿色
TD.110720 2020 625 1.6 – 2.7 TD.130141红色
TD.09651 2019 625 1.6 – 2.7 TD.09761绿色
TD.02503 2016 625 1.6 – 2.7 TD.140263蓝色
TD.00426 2014 625 1.6 – 2.7 TD.07382红色
传统饮食基础
产品编号 基础饮食 强力霉素透明
每公斤饲料毫克		 每日强力霉素
3-5克日粮中的毫克		 替代
食用色素
TD.05125 7012 625 1.6 – 2.7 TD.08434蓝色
TD.98186 7012 200 0.5 – 0.9 红色

与给水相比，饮食分娩是许多研究人员的一个更好的选择。

  • 饮食能保护身体免受光线伤害。水可能必须用深色或铝箔包装的瓶子浇水。
  • 饮食通常每周改变一次。水可能需要每隔几天更换一次。
  • 饮食供应也可以减少脱水的风险，并避免需要给予蔗糖(考索恩等)。艾尔。(2007年)

含有多西环素的饮食经常以辐照形式订购。辐照必须在订购时要求，并将增加大约两周的准备时间。

如果你的工作需要不含苜蓿的食物进行荧光成像，可以考虑使用全球啮齿动物的饮食基础。如果需要进一步的成像清晰度，我们可以用多西环素进行纯化饮食。

联系我们根据您的具体需求，我们可以推荐一个现有的产品代码或创建一个新的配方。

Doxycycline diets | Envigo

Envigo Teklad diets makes a variety of doxycycline containing diets for your Tet regulated systems. A range of levels of doxycycline (as doxycycline hyclate) can be added. Typical inclusion rates are 200 and 625 mg/kg diet, but some researchers specify a higher or lower level.

Diets are easily customizable as they are made fresh when ordered. We currently have over 150 different doxycycline formula combinations. We likely have an existing product number to meet your specifications. Specifications include: base diet, concentration of doxycycline, and food coloring.

Global diet base
Product number Base diet Doxycycline hyclate
mg per kg diet		 Daily doxycycline
mg in 3-5 g diet		 Alternative
with food coloring
TD.01306
stocked		 2018 625 1.6 – 2.7 TD.08541Red
TD.120769Blue
TD.00502 2018 200 0.5 – 0.9 TD.04104Green
TD.110720 2020 625 1.6 – 2.7 TD.130141Red
TD.09651 2019 625 1.6 – 2.7 TD.09761Green
TD.02503 2016 625 1.6 – 2.7 TD.140263Blue
TD.00426 2014 625 1.6 – 2.7 TD.07382Red
Traditional diet base
Product number Base diet Doxycycline hyclate
mg per kg diet		 Daily doxycycline
mg in 3-5 g diet		 Alternative
with food coloring
TD.05125 7012 625 1.6 – 2.7 TD.08434Blue
TD.98186 7012 200 0.5 – 0.9 Red

Compared to water delivery, diet delivery is a preferable option for many researchers.

  • Diet offers protection from light. Water may have to be given in dark-colored or foil-wrapped bottles
  • Diet is typically changed once per week. Water may need to be changed every few days
  • Diet delivery may also reduce risk of dehydration and preclude the need to give with sucrose (Cawthorne et. al. 2007)

Doxycycline containing diets are often ordered in irradiated form. Irradiation must be requested at the time of ordering and will add approximately two weeks to the lead time.

If your work requires an alfalfa-free diet for fluorescent imaging, consider using a global rodent diet base. If further imaging clarity is needed, we can make purified diets with doxycycline.

 

harlan teklad官网动物饲料代理商 药物饮食 TD.130755伊维菌素 TD.01432芬苯达唑

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harlan teklad官网动物饲料代理商 药物饮食 TD.130755伊维菌素 TD.01432芬苯达唑

药物饮食

特克拉德药物实验室动物饮食是在一个附属工厂或在我们的定制研究饮食设施生产。与客户服务部门或当地Envigo客户代表联系，了解库存饮食的定价和供应情况。联系营养师讨论这些或其他药物饮食的定制版本。

药物饮食必须按照兽医的指示使用。

含药啮齿动物饲料
主要目的 产品代码 药物治疗 浓度 基础饮食 包装
毛螨处理 TD.130755 伊维菌素 百万分之十二 2018 25磅包-辐照
粉螨治疗 TD.01432 芬苯达唑 百万分之150 2008 S 25磅包-辐照*
50磅包-高压釜
肺孢子虫p肺炎
预防		 TD.06596 Uniprim® 275 ppm甲氧苄啶
1365 ppm磺胺嘧啶		 2018 25磅包-辐照*

伊维菌素定制饮食®，芬苯达唑是可行的。修改包括：不同的基础饮食，染色与食物染料，以及其他剂量的浓度，根据您的独特要求。联系营养师来讨论你的需求。

其他药物和化合物，如强力霉素和他莫昔芬可以添加到我们的定制研究饮食设施的饮食。访问我们的定制研究饮食网站或联系我们以获得更多信息。

Medicated diets | Envigo

Teklad medicated lab animal diets are manufactured either at a subsidiary plant or at our custom research diet facility. Contact customer service or your local Envigo account representative for pricing and availability of stocked diets. Contact a nutritionist to discuss customized versions of these or other medicated diets.

Medicated diets must be used as directed by a veterinarian.

Stocked medicated rodent diets
Primary Purpose Product Code Medication Concentration Base diet Packaging
Fur mite treatment TD.130755 Ivermectin 12 ppm 2018 25 lb bag- irradiated
Pinworm treatment TD.01432 Fenbendazole 150 ppm 2018S 25 lb bag- irradiated*
50 lb bag- autoclavable
Pneumocystis pneumonia
prevention		 TD.06596 Uniprim® 275 ppm trimethoprim
1365 ppm sulfadiazine		 2018 25 lb bag- irradiated*

Custom diets with Ivermectin, Uniprim®, and Fenbendazole are available. Modifications include: different base diet, coloring with food dyes, and other dosing concentrations based on your unique requirements. Contact a nutritionist to discuss your needs.

Other medications and compounds such as doxycycline and tamoxifen may be added to diets at our custom research diet facility. Visit our custom research diets site or contact us for additional information.

harlan Teklad diet, bedding and enrichment 饮食、垫料和营养丰富动物饲料

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harlan Teklad diet, bedding and enrichment 饮食、垫料和营养丰富动物饲料

饮食、垫料和营养丰富

你的研究成果在很大程度上取决于你的研究模型是什么。确保你的研究动物有最适当的饮食是保持一致，可靠的研究数据的关键。你是否需要一个标准啮齿动物饮食或者是定制研究饮食，我们知道如何提供健全的营养解决方案。

依靠我们对你的研究和动物福利的承诺来保护你工作的潜力。了解Envigo实验室动物饮食如何帮助您提高您的研究：

通过提供全方位的实验动物饮食，床上用品和丰富，Envigo作为您的研究需求的一站式供应商。

折叠所有标签

各种实验室动物的标准天然成分饮食由谷物、植物和动物蛋白质等农产品组成。这些食物被用来满足动物群体在繁殖、生长和维持方面的日常需要。如果仔细选择，它们也可以支持许多研究目标。

所有特克拉德标准天然配料饮食的特点是我们的固定配方理念，加上严格的配料采购实践，然后是自动化和受控的生产实践。常规的，可蒸压的，认证的，和辐照实验日粮是众多选择之一。

了解更多关于标准天然成分饮食的知识

如果你需要控制营养，诱发疾病或提供特定剂量的饮食，你可以利用我们的经验，净化或其他类型的定制研究饮食。我们的营养学家可以与您独特的规格，以找到一个符合您的研究要求的特克乐解决方案。

了解更多关于定制研究饮食的信息

为了治疗一种疾病或预防疾病或暴发，使用由兽医指导的特克勒德药物饮食可以支持储存的药物饮食。定制饮食与各种药物或化合物也可以添加在我们的定制研究饮食设施的要求。

What comes out of your research depends in large part on what goes into your research models. Ensuring your study animals have the most appropriate diet is critical to maintaining consistent, reliable research data. Whether you need a standard rodent diet or a custom research diet, we know how to provide sound nutrition solutions.

Protect the potential of your work by relying on our commitment to your research and animal welfare. Learn how Envigo laboratory animal diets can help advance your studies with:

By providing a full range of lab animal diets, bedding and enrichment, Envigo serves as your one-stop supplier for your research needs.

COLLAPSE ALL TABS

Standard natural ingredient diets for a variety of laboratory animal species are comprised of agricultural commodities such as grains, and plant and animal proteins. These diets are used to meet the everyday needs of animal colonies for breeding, growth and maintenance. When carefully chosen, they also can support many research objectives.

The hallmark of all Teklad standard natural ingredient diets is our fixed formulation philosophy coupled with stringent ingredient procurement practices, followed by automated and controlled manufacturing practices. Regular, autoclavable, certified, and irradiated laboratory diets are among the many options.

Learn more about standard natural ingredient diets

If you need to control nutrients, induce disease or provide specific doses through a diet, you can leverage our experience with purified or other types of custom research diets. Our nutritionists can work with your unique specifications to find a Teklad solution that meets your study’s requirements.

Learn more about custom research diets

For treatment of a condition or to prevent illness or outbreak, the use of Teklad medicated diets as directed by a veterinarian can be supported by stocked medicated diets. Custom diets with various medications or compounds can also be added by request at our custom research diet facility.

Learn more about medicated diets

From contact bedding to custom-cut paper cage liners to enrichment products, we can support your laboratory animals with a variety of comprehensive solutions.

Learn more about bedding and environmental enrichment products

Harlan teklad官网动物饲料 Dog diets 狗的饮食饲料

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Harlan teklad官网动物饲料 Dog diets 狗的饮食饲料

特克拉德狗的饮食是完整的固定配方饮食，旨在提供狗所需的所有基本营养，以实现有效的生长，维护和繁殖。补充膳食补充剂是不必要的。从几种饮食中选择最能满足你需要的食物。

特克拉德全球狗饮食是一个综合系列的蛋白质，脂肪和卡路里水平调整，以优化性能在特定的生命阶段。它们包括家禽副产品膳食，这是一种比传统肉类和骨粉更好的动物蛋白质来源。

动物和植物来源的蛋白质提供了必需氨基酸的适当平衡，以维持狗的整个生命周期的有效运作。高质量的动物脂肪是浓缩能量和必需脂肪酸的极好来源，以促进和支持研究犬、哺乳母犬和生长幼犬的一般状况。脂肪还能增强适口性。

特克拉德狗的饮食是加强适当的数量和平衡的维生素和矿物质，以帮助调节身体系统和体液，加强牙齿和骨骼，并保持良好的血液，皮肤和皮毛状况。这些饮食是为了帮助分解淀粉而挤压出来的。这就提高了消化率和适口性。

Teklad dog diets are complete fixed formula diets designed to provide all essential nutrients required by dogs to achieve efficient growth, maintenance and reproduction. Additional dietary supplements are unnecessary. Choose from several diets to best meet your needs.

Teklad global dog diets are an integrated series with protein, fat, and calories levels adjusted to optimize performance at specific life stages. They include poultry by-product meal, an improved source of animal protein over conventional meat and bone meals.

Protein from animal and plant sources provides the proper balance of essential amino acids to maintain efficient functioning of the dog’s body throughout its life cycle. High-quality animal fat is an excellent source of concentrated energy and essential fatty acids required to promote and support the general condition of research dogs, lactating bitches, and growing puppies. Fat also enhances palatability.

Teklad dog diets are fortified with the proper amounts and balance of vitamins and minerals required to help regulate body systems and fluids, strengthen teeth and bones, and maintain good blood, skin, and coat condition. The diets are extruded to help break down starches. This results in improved digestibility and palatability.

Products
Teklad dog diets Non-autoclavable form
Teklad global 21% protein dog diet 2021, 2021C
Teklad global 25% protein dog diet 2025, 2025C
Teklad global 27% protein dog diet 2027, 2027C
Teklad 21% lab dog diet 8755
Teklad 25% lab dog diet 8653, 8727C
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

COLLAPSE ALL TABS

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.

Recommended storage conditions:

  • Cool and dry; at or below 70 degrees Fahrenheit, humidity below 50% ideal, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

Teklad Dog Diets are designed to be fed to dogs under research conditions. Select the feeding method which keeps the animal in the proper body condition. The amount of food the research dog needs depends upon its size, age, breed, temperament, and amount of exercise.

Feed the pregnant female twice a day or ad libitum. Moisten the diet for her first few feedings after delivery. Thereafter, allow ad libitum access to diet and also feed her moistened food once a day.

Puppies will start eating diet (either moistened or dry) when they are about four weeks old. To encourage them to eat, add one cup water to each cup of dog food. Initially, feed the moistened food three times daily. The daily feedings (either dry or moistened) can be reduced to two as the puppies grow. The self-feeding program is ideal for puppies since they like to chew on dry food. They also can eat when they are hungry, assuring proper and adequate nutrition.

harlan teklad官网动物饲料代理商 他莫昔芬饮食 Tamoxifen diets TD.130855

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harlan teklad官网动物饲料代理商

他莫昔芬饮食 harlan teklad官网动物饲料代理商 他莫昔芬饮食 Tamoxifen diets TD.130855

他莫昔芬激活Creer的饮食

有几篇文献引用了含有他莫昔芬的饮食对CRE模型在雌激素受体突变的控制下的应用。恩维戈特克乐饮食使各种含他莫昔芬的饮食定制，以满足您的研究需要。我们还制作了各种各样的含多西环素饮食对于被监管的系统。如果你有任何问题，请咨询营养师。

枸橼酸他莫昔芬和他莫昔芬

他莫昔芬作为他莫昔芬-蔗糖混合物添加到饮食中.鼓励用户使用库存供应。然而，泰克乐将继续与客户准备的混合。如果您选择此选项，请咨询营养师，以获得有关配制和发送混合物的更多信息。

鼓励用户从以下库存选项中进行选择，以便在几天内随时可供装运。

特克乐提供USP级三苯氧胺和枸橼酸他莫昔芬的饮食。
他莫昔芬
每公斤饲料毫克		 日他莫昔芬
每公斤体重毫克1		 饮食编码
(特克勒德供应他莫昔芬)
    天然色 红色
250 40 TD.130855 TD.130856
500 80 TD.130857 TD.130858
400柠檬酸盐2 40 TD.130859 TD.1308603

1假设体重20-25克，摄入量3-4克。
2枸橼酸他莫昔芬为66%他莫昔芬
3在欧洲称为TAM 400/Creer(TD.55125)

请为辐照饮食增加5-10天的准备时间；库存和定制产品至少需要3公斤订单。

这些饲料都有他莫昔芬与~5%蔗糖预混合，作为一种适口性增强剂；然而，饲料厌恶仍有可能发生。如果摄入是一个问题，请参阅下面的建议。

TeculadGlobal2016-这些例子中的基础饮食-仅仅是少数几种植物雌激素饮食中的一种。咨询营养学家关于其他基础饮食的使用。

折叠所有标签

  • 最低订货量为3公斤，足以喂养20只小鼠一个月。
  • 储存冷冻饮食，并计划在六个月内使用。
  • 典型的准备时间为两周(如果经过辐照，则为四周)
  • 辐照(可选)20 kGy的最低剂量(必须按顺序要求)
  • 订购：请致电800.483.5523或在线启动订单

计划：

  • 最初减少食物摄入量和减肥
  • 日常观察动物的耐受性-咨询您的IACUC监测指标。
  • 必要时进行干预

如果摄入似乎是一个问题：

  • 通过进行他莫昔芬给药试验，确定低剂量对你的模型是否有效。
  • 用含他莫昔芬颗粒与常规饲料颗粒混合逐渐驯服小鼠
  • 把食物弄湿，然后放在笼子里的盘子里(需要每天更换)。
  • 平日喂饲他莫昔芬饮食，周末有规律饮食。
  • 每隔一周(三苯氧胺饮食两周，休息一周)进行更长时间的治疗
  • 他莫昔芬是一种选择性雌激素受体调节剂(SERM)，这意味着它可以抑制雌激素的作用或具有促进雌激素的作用。
  • 人体治疗效果的一般剂量为20毫克/天。用于啮齿动物的他莫昔芬饮食通常含有~1至2毫克/粒。
  • 当处理饮食时，可以使用典型的实验室预防措施，如实验室外套、手套和面罩，尽量减少接触他莫昔芬的事故。
  • 您的化学品安全部门应联系，以获得更多的机构特定的指导方针，以处理和处置含有他莫昔芬的饮食。
  • 治疗时间从一周到两周不等。1,2,5,6,7,8一至两个月3,4,8
  • 纯他莫昔芬1,5,8和枸橼酸他莫昔芬1,2,3,4,6,7都是有效的
  • 通常他莫昔芬剂量为每天40-80毫克/公斤体重。
  • 纯他莫昔芬的典型包合物为250 mg。8或500毫克1,5枸橼酸他莫昔芬为每公斤400毫克。1,2,3,4,6,7
  • 报告的初始重量损失为10%。1,2,4,7,8，与食物摄入量减少有关2
  • 恢复正常饮食后体重的恢复可能会因基因失活而受损。2,7
  1. 安德森·KB，Winer LH，Mork HK，Molkentin JD，Jaisser F.2010。他莫昔芬诱导CRE介导的小鼠心脏基因断裂的给药途径和剂量。 转基因RES 19：715-725。
  2. 蒋介明，凌杰，郑永赫，价格DL，Aja SM，Wong PC.2010年。TDP-43的缺失下调了与肥胖相关的基因Tbc1d1，并改变了身体的脂肪代谢。 美国Acad Sci美国：16320-16324。
  3. Kardakaris R.，Gareus R.，Xandomlea S，Pasparakis M.2011。内皮和巨噬细胞特异性P38αMAPK缺乏不影响ApoE-/-小鼠动脉粥样硬化的发病机制。 PLOSOne 6：e21055。
  4. [2]Kiermayer C，Conrad M，Schneider M，Schmidt J，Brielmeier M.枸橼酸他莫昔芬口服对小鼠心脏时空基因灭活的优化。 创世纪45：11-16。
  5. Koitabashi N，Bedja D，Zaiman AL，Pinto Ym，Zhang M，Gabrielson KL，Takimoto E，Kass DA。2009年。心肌细胞靶向他莫昔芬诱导MerCreMer基因缺失模型中短暂性心肌病的避免。 中国保监会第105：12-15号决议
  6. Kratsios P，Catela C，Salimova E，Huth M，Berno V，Rosenthal N，Morkioti F.2009。细胞自主Notch信号在胚胎和成年心脏心肌细胞中的独特作用。 PCirc第106：559-572号决议。
  7. Miro-Murillo M，Elorza A，Soro-ArNaiz I，Albacete-Albacete L，Ordonz A，Balsa E，Vara-Vega A，Vazquez S，Fuertes E，Fernandez-Criado C，Landazuri MO，Aragones J.2011。急性VHL基因失活可诱导心脏HIF依赖的促红细胞生成素基因表达. PLOS One 6：E 22589。
  8. Welle S，Burgess K，Thornton CA，Tawil R.2009。成熟小鼠肌生长抑素耗竭程度与肌肉生长的关系。 李玉玲.医学杂志.1997(4)：E 935-40.

Tamoxifen diets

Diets with tamoxifen activate CreER

Several references cite use of tamoxifen-containing diets for models with Cre under the control of a mutated estrogen receptor. Envigo Teklad diets makes a variety of tamoxifen-containing diets customized to meet your research needs. We also make a variety of doxycycline-containing diets for tet regulated systems. If you have any questions, don’t hesitate to consult a nutritionist.

Teklad stocks tamoxifen and tamoxifen citrate

Tamoxifen is added to the diet as a tamoxifen-sucrose mixture. Users are encouraged to use the stocked supply. However, Teklad will continue to work with customer prepared mixes. If you choose this option, please consult a nutritionist for additional information about preparing and sending the mixture.

Users are encouraged to select from the stocked options below supply readily available to ship within days.

Teklad offers diet with USP grade tamoxifen and tamoxifen citrate
Tamoxifen
mg per kg diet		 Daily tamoxifen
mg per kg body weight1		 Diet code
(Teklad supplied tamoxifen)
    Natural colored Red
250 40 TD.130855 TD.130856
500 80 TD.130857 TD.130858
400 citrate2 40 TD.130859 TD.1308603

1 Assumes 20-25 g body weight and three-four g intake
2 Tamoxifen citrate is 66% tamoxifen
3 Referred to as TAM400/CreER in Europe (TD.55125)

Please add 5-10 day lead time for irradiated diets; minimum 3 kg orders are required for stocked and customized items.

These diets all have tamoxifen premixed with ~five percent sucrose as a palatability enhancer; however, feed aversion may still occur. If intake is a problem, see below for advice.

Teklad Global 2016 — base diet in these examples — is only one of several minimal phytoestrogen diets Teklad produces. Consult a nutritionist about use of other base diets.

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  • Minimum order quantity is three kg, sufficient for feeding ~20 mice for one month
  • Store diet refrigerated and plan to use within six months
  • Typical lead time is two weeks (four weeks if irradiated)
  • Irradiation (optional) minimal dose of 20 kGy (Must be requested at time of order)
  • To place an order: contact Teklad Customer Service at 800.483.5523 or initiate order online

Plan for:

  • Initial reduction in food intake and weight loss
  • Daily observation of animal tolerance — consult your IACUC for monitoring metrics
  • Intervene when necessary

If intake seems to be a problem:

  • Determine if a lower dose is effective for your model by conducting a tamoxifen dose feeding trial
  • Gradually acclimate mice by mixing tamoxifen-containing pellets with regular feed pellets
  • Wet the food, then place in a dish inside the cage (requires daily replacement)
  • Feed tamoxifen diet on weekdays, regular diet on weekends
  • Alternate weeks (two weeks on tamoxifen diet, one week off) for longer treatments
  • Tamoxifen is a selective estrogen receptor modulator (SERM) meaning it can repress actions of estrogen or have pro-estrogen effects
  • Usual dose for therapeutic effects in humans is 20 mg/day. Tamoxifen diets for rodents typically contain ~one to two mg/pellet
  • Accidental tamoxifen exposure can be minimized by using typical lab precautions of lab coat, gloves, and mask when handling the diet.
  • Your chemical safety department should be contacted for additional institution specific guidelines for handling and disposal of tamoxifen containing diets.
  • Length of treatment varies from one to two weeks1,2,5,6,7,8 to one to two months3,4,8
  • Pure tamoxifen1,5,8 and tamoxifen citrate1,2,3,4,6,7 are both effective
  • Usual tamoxifen doses are ~40-80 mg per kg body weight per day
  • Typical inclusion for pure tamoxifen is 250 mg8 or 500 mg1,5 and for tamoxifen citrate is 400 mg per kg diet1,2,3,4,6,7
  • Initial weight loss of ten % is reported1,2,4,7,8, associated with reduced food intake2
  • Subsequent recovery of body weight after returning to regular diet may be compromised by gene inactivation2,7
  1. Andersson KB, Winer LH, Mork HK, Molkentin JD, Jaisser F. 2010. Tamoxifen administration routes and dosage for inducible Cre-mediated gene disruption in mouse hearts. Transgenic Res 19:715-725.
  2. Chiang PM, Ling J, Jeong YH, Price DL, Aja SM, Wong PC. 2010. Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proc Natl Acad Sci USA 107:16320-16324.
  3. Kardakaris R, Gareus R, Xanthoulea S, Pasparakis M. 2011. Endothelial and macrophage-specific deficiency of P38alpha MAPK does not affect the pathogenesis of atherosclerosis in ApoE-/- mice. PLoS One 6:e21055.
  4. Kiermayer C, Conrad M, Schneider M, Schmidt J, Brielmeier M. 2007. Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrate. Genesis 45:11-16.
  5. Koitabashi N, Bedja D, Zaiman AL, Pinto YM, Zhang M, Gabrielson KL, Takimoto E, Kass DA. 2009. Avoidance of transient cardiomyopathy in cardiomyocyte-targeted tamoxifen-induced MerCreMer gene deletion models. Circ Res 105:12-15.
  6. Kratsios P, Catela C, Salimova E, Huth M, Berno V, Rosenthal N, Mourkioti F. 2009. Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart. PCirc Res 106:559-572.
  7. Miro-Murillo M, Elorza A, Soro-Arnaiz I, Albacete-Albacete L, Ordonez A, Balsa E, Vara-Vega A, Vazquez S, Fuertes E, Fernandez-Criado C, Landazuri MO, Aragones J. 2011. Acute Vhl gene inactivation induces cardiac HIF-dependent erythropoietin gene expression. PLoS One 6:e22589.
  8. Welle S, Burgess K, Thornton CA, Tawil R. 2009. Relation between extent of myostatin depletion and muscle growth in mature mice. Am J Physiol Endocrinol Metab.Oct;297(4):E935-40.

Harlan teklad官网动物饲料 Swine diets猪日粮 国内动物饲料定制

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Harlan teklad官网动物饲料 Swine diets猪日粮 国内动物饲料定制

特克拉德猪日粮是一种特殊配方的天然饲料，旨在提供对猪的生长、维持和繁殖至关重要的所有已知营养素的适当平衡。

特克勒德猪日粮通过固定配方日粮提供统一的营养，以尽量减少营养差异，否则，如果饲料的成分组成从一批改变到下一批。

由鱼类和植物来源提供的蛋白质，再加上补充氨基酸，提供了研究猪所需必需氨基酸的适当数量和平衡。

特克勒德猪的饮食适当强化维生素和矿物质，以帮助支持调节体液和适当的身体系统的功能，以确保足够的生长，维护和繁殖的研究猪。

特克拉德猪的饮食配方和制造没有人工防腐剂，抗结块剂，或其他添加剂，否则可能影响某些类型的研究结果。

产品
特克勒德猪日粮 不可蒸压式
美酒饮食 7037、7037 C
特克勒德素食猪/母猪种植者饮食 7200
美酒饮食 8753、8753 C
并不是所有的产品都是在当地库存的，可能需要延长交货期和额外的费用。
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时，一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存，可以根据要求提供认证。可适用最低订货量和附加费用。
折叠所有标签

没有一个确定的点，人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲，当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月，有时甚至在生产后12个月。这种实践经验，随着时间的推移，再加上文献支持和维生素测试，让我们相信，这些饮食继续支持动物的健康和研究的完整性，至少在9个月后生产。如果你不确定当地的政策，请向你的机构寻求指导。

建议的储存条件：

  • 凉爽和干燥；在华氏70度或以下，湿度最好在50%以下，但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中，防止连续暴露于光线下，并将空气暴露在最小范围内。

应该允许断奶的猪[医]锂节食的机会。成年人应该以每天体重的百分之二到百分之三的速度喂食。新鲜的干净的水应该总是可用的。

Teklad swine diets are natural-ingredient diets specifically formulated to provide the proper balance of all known nutrients considered essential for the growth, maintenance, and reproduction of swine.

Teklad swine diets provide uniform nutrition through fixed-formula diets designed to minimize the nutrient variances that otherwise could occur if the ingredient composition of the diets were altered from one batch to the next.

Protein supplied by fish and plant sources combined with supplemental amino acids provides the proper amount and balance of essential amino acids required by research swine.

Teklad swine diets are fortified appropriately with vitamins and minerals to help support the regulation of body fluids and the proper functioning of the body system to ensure adequate growth, maintenance, and reproduction of research swine.

Teklad swine diets are formulated and manufactured without artificial preservatives, anti-caking agents, or other additives that otherwise may influence the results of certain types of research studies.

Products
Teklad swine diets Non-autoclavable form
Teklad miniswine diet 7037, 7037C
Teklad vegetarian pig/sow grower diet 7200
Teklad miniswine diet 8753, 8753C
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

COLLAPSE ALL TABS

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.

Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit with humidity ideally below 50%, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

Weaning pigs should be allowed ad libitum access to diet. Adults should be fed at a rate of two percent to three percent of their body weight per day. Fresh, clean water should always be available.

Harlan teklad官网动物饲料 Primate diets 灵长类饮食 国产动物饲料定制

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Harlan teklad官网动物饲料 Primate diets 灵长类饮食 国产动物饲料定制

特克拉德灵长类饮食是固定的配方饮食，以提供适当的营养平衡所需的新世界和旧世界灵长类动物的所有品种和年龄。饮食是为了提供统一的实验和生产结果而制定的。

植物、牛奶和鱼类蛋白质来源的结合提供了必需氨基酸的适当数量和平衡，以维持研究灵长类在其整个生命周期和研究功能中的物理状况。

高质量的脂肪来源提供了生长、维持和繁殖所需的必需脂肪酸的平衡。这些脂肪来源也提供了一种高可消化的能源。

特克拉德灵长类饮食强化维生素和矿物质，包括维生素D 3，以适当的骨发育和维生素C预防坏血病和贫血。稳定维生素C(L-抗坏血酸-2-聚磷酸)用于延长保质期.饮食是营养完整和平衡的，因此额外的饮食补充剂是不必要的。

特克拉德灵长类食物被挤压出来，以帮助分解淀粉，提高消化率和适口性。喂食高可消化的膨化食物会产生坚固的大便，这有助于减少清洗时间。

产品
特克拉德灵长类食物 不可蒸压式
全球20%蛋白质灵长类食物 2050
特克乐全球25%蛋白质灵长类食物 2055
高纤维灵长类食物 7195
15%猴子饮食 8714
15/10高纤维猴子饮食 8788
新世界灵长类食物 8794
并不是所有的产品都是在当地库存的，可能需要延长交货期和额外的费用。
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时，一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存，可以根据要求提供认证。可适用最低订货量和附加费用。
折叠所有标签

没有一个确定的点，人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲，当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月，有时甚至在生产后12个月。这种实践经验，随着时间的推移，再加上文献支持和维生素测试，让我们相信，这些饮食继续支持动物的健康和研究的完整性，至少在9个月后生产。如果你不确定当地的政策，请向你的机构寻求指导。

建议的储存条件：

  • 凉爽和干燥；在华氏70度或以下，湿度最好在50%以下，但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中，防止连续暴露于光线下，并将空气暴露在最小范围内。

一般来说，非人类灵长类动物将消耗相当于其体重百分之四的食物，但是有许多因素可以影响日常消费，包括物种、生命阶段、住房和环境条件。少量的水果、蔬菜或坚果可以作为环境丰富的食物。清洁的淡水应始终可用。

Teklad primate diets are fixed-formula diets formulated to provide the proper balance of nutrients required by new-world and old-world primates of all breeds and ages. Diets are formulated to provide uniform experimental and production results.

A combination of plant, milk and fish protein sources supplies the proper amounts and balance of essential amino acids necessary to maintain the physical condition of research primates throughout their life cycle and research function.

High-quality fat sources provide the balance of essential fatty acids required for growth, maintenance, and reproduction. These sources of fat also provide a highly digestible source of energy.

Teklad primate diets are fortified with vitamin and minerals including vitamin D3 for proper bone development and vitamin C for prevention of scurvy and anemia. Stabilized vitamin C (L-ascorbyl-2-polyphosphate) is used to extend the shelf life. Diets are nutritionally complete and balanced making additional dietary supplements unnecessary.

Teklad primate Diets are extruded to help break down starches, improving digestibility and palatability. Feeding highly digestible extruded diets results in firm stools, which helps reduce cleaning time.

Products
Teklad primate diets Non-autoclavable form
Teklad global 20% protein primate diet 2050
Teklad global 25% protein primate diet 2055
Teklad hi-fiber primate diet 7195
Teklad 15% monkey diet 8714
Teklad 15/10 hi-fiber monkey diet 8788
Teklad new world primate diet 8794
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

COLLAPSE ALL TABS

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.

Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit with humidity ideally below 50%, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

In general, nonhuman primates will consume an amount of diet equal to four percent of their body weight but there are many factors that can affect daily consumption including species, life-stage, housing, and environmental conditions. Small amounts of fruits, vegetables, or nuts may be fed as environmental enrichment. Clean fresh water should always be available.

harlan teklad官网动物饲料代理商 基础饲料 TD.00235基础配料 TD.88232基础混合

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harlan teklad官网动物饲料代理商 基础饲料 TD.00235基础配料 TD.88232基础混合

您可能需要在您自己的设施中添加一些特定的成分。在这种情况下，Envigo提供的基本混合，从设计上来说，是额外包含的起点。当你选择基本的混合饮食时，你只需按你所需的特定比例添加任何成分。在我们的基础组合中的营养水平被调整，以考虑稀释添加的成分(S)，以便最终完整的饮食包含所需的营养水平。

  • TD.00235基础配料(93%)；无脂肪Aln-93g
  • TD.88232基础混合(不含20%油)

下面是一些基本组合对您有帮助的例子：

  • 将脂肪源的全部或一部分排除在外。最终用户可以添加各种脂肪，并从一个基础混合物中进行多种饮食。
  • 根据需要为不稳定、危险或有限的供应成分制定新鲜饮食。
  • 在相同的基础组合中加入不同的维生素或矿物质混合物，以创造一系列维生素或矿物质调整饮食。

如果有适当的混合设备，并且你有能力喂粉饮食，基础混合提供灵活性和经济性。

You may want to add some specific ingredients in your own facility. In that case, Envigo provides basal mixes that are, by design, a starting point for additional inclusions. When you choose a basal mix diet, you simply add any ingredient(s) in a specific proportion that your require. The nutrient levels in our basal mix are adjusted to account for the dilution of the added ingredient(s), so that the final complete diet contains the desired nutrient levels.

  • TD.00235      Basal mix (93%); AIN-93G without fat
  • TD.88232      Basal mix (without 20% Oil)

Here are some examples of how a basal mix could be helpful to you:

  • Leave all or a portion of the fat source out. The end user can add various fats and make multiple diets from one basal mix
  • Make fresh diet as needed for an unstable, hazardous, or limited supply ingredient
  • Add a different vitamin or mineral mix to the same basal mix to create a series of vitamin or mineral adjusted diets

If proper mixing equipment is available, and you have the capability to feed powder diet, basal mixes offer flexibility and economy.

harlan teklad官网动物饲料 兔子 猪 几内亚猪 仓鼠、沙土鼠 TD.92033猪日粮

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The most common custom rabbit diets are those with a standard diet base and added cholesterol. Typically, the added cholesterol ranges from 0.25% to two percent. Additional fat can also be a feature of these formulas. To preserve pellet quality we recommend no more than six percent additional fat. Added fat is most often supplied as peanut oil, corn oil, coconut oil, or a combination. We recommend the Teklad base diets 2030 or 2031.

Rabbits do not readily consume purified diet. When specific nutrient manipulations are necessary, hybrid diets or at least some alfalfa meal inclusion is recommended. Contact us for formula examples or to discuss your specific needs.

Most often, customized diets for swine feature natural ingredients with added fat and cholesterol. Here are three variations on this theme:

  • TD.92033      Swine diet (15% lard, 1.2% cholesterol)
  • TD.92052      Swine diet (15% lard, 1.5% cholesterol)
  • TD.93296      Swine diet (15% lard, two perecent cholesterol)

We recommend these diets in meal/powder form, as pellets are not very durable. Other natural ingredient and purified diets with various nutrient manipulations are available. Contact us for further information.

The most common custom Guinea pig diets are those with a standard diet base (such as Teklad 2040 or 2041) and added cholesterol.

Guinea pigs do not readily consume purified diets, so when specific nutrient manipulations are necessary, hybrid diets (mixture of refined and natural ingredients) are recommended. At the very least it is advisable to retain some alfalfa meal in the diet. Contact us for further information.

Most times, diets that are developed for mice and rats are suitable for hamsters and gerbils, and vice versa. We may advise increasing specific nutrients in a purified diet for hamsters and gerbils. Contact us for further information.

Depending on the focus of your research, customized diet for non-human primates can contain natural ingredients, refined ingredients, or a mixture of both.  Custom diets for primates often feature adjustments in fat type, fat level, and cholesterol. Contact us for further information.

harlan teklad官网代理商 动物饲料 AIN饮食配方 TD.00102 AIN-93m TD.94045 AIN-93g

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harlan teklad官网代理商 动物饲料 AIN饮食配方 TD.00102 AIN-93m TD.94045 AIN-93g

AIN饮食配方Envigo

这些配方是含有常用精制成分的纯正饮食。这些基本配方通常是为特定的研究目的而修改的，例如改变脂肪来源、维生素或矿物质水平，或添加一种化合物。见常见问题了解更多关于这些公式的历史的章节，AIN-76A，AIN-93g，和AIN-93m。

这些配方(以及其他纯化饲料)不含苜蓿，可用于减少背景自荧光在某些成像应用中。我们的全球啮齿动物饮食也是无苜蓿的，适合成像工作.有关这些公式或修改的进一步信息，请与我们联系。

其他相关产品代码：

  • TD.94096适合辐照的AIN-76A版本(维生素含量增加)
  • TD.97184适合辐照的an-93g版本(维生素含量增加)
  • TD.00102AIN-93m适合辐照的版本(维生素含量增加)
  • TD.95092用玉米油代替大豆油的n-93g改性。

AIN diet formulas | Envigo

These formulas are purified diets with commonly used refined ingredients. These basic formulas are often modified for a specific research purpose, such as altering the fat source, a vitamin or mineral level, or adding a compound. See the FAQ section to learn more about the history of these formulas, AIN-76A, AIN-93G, and AIN-93M.

These formulas (as well as other purified diets) do not contain alfalfa and can be used to reduce background autofluorescence in certain imaging applications. Our Global Rodent Diets are also alfalfa-free and are suitable for imaging work. Please contact us for further information about these formulas or modifications.

Other related product codes:

  • TD.94096  version of AIN-76A suitable for irradiation (vitamin levels are increased)
  • TD.97184  version of AIN-93G suitable for irradiation (vitamin levels are increased)
  • TD.00102  version of AIN-93M suitable for irradiation (vitamin levels are increased)
  • TD.95092  modification of AIN-93G where soybean oil is replaced with corn oil.