食品级茶黄色素 天然食用茶黄色素 100g

茶黄色素  100g/瓶
上海金畔生物科技有限公司
茶黄色素为黄色或橙黄色粉末,易溶于水和乙醇水溶液.不溶于氯仿和石油醚。具有抗氧化性,其抗氧化性可与维生索C、BHA、BHT相比。茶黄色索为酸性色素,在PH4.6—7.0范围内色泽较好。
茶黄素又称为茶黄素,是存在于红茶中的一种金黄色色素,是茶叶发酵的产物。在生物化学上,茶黄素是一类多酚羟基具茶骈酚酮结构的物质。茶黄素占干茶重量的 0.5%到2%,取决于红茶加工的方法。茶黄素在茶汤中鲜亮的颜色和浓烈的口感方面,起到了一定的作用,是红茶的一个重要的质量指标。茶黄素是第一次从茶叶中找到具有确切药理作用的化合物。

我国《食品添加剂使用卫生标准》(GB2760―1996)中规定:可在果蔬汁(味)饮料类、配制酒、糖果、糕点上彩装、红绿丝、奶茶、果茶中按生产需要适量使用。另外在汽水、糖果、糕点中的使用量约0.4g/kg

Himedia 链球菌培养基 Media for Streptococci

Himedia 链球菌培养基 Media for Streptococci
上海金畔生物科技有限公司,作为HiMedai公司在中国的代理商,在微生物培养和检测领域,会一如既往地为您带来优质的服务。
Himedia代理,欢迎新老客户访问Himedia官网或者咨询我们获取更多有关产品信息。
Himedia 链球菌培养基 Media for Streptococci
The bacterium considered as opportunistic pathogens of mammals can be isolated and cultivated on media. To serve this purpose, HiMedia has developed a range of media such as Azide Blood Agar Base, Columbia C.N.A Agar Base etc.
这种细菌被认为是哺乳动物的机会致病菌,可以在培养基上分离和培养。为了达到这一目的,HiMedia开发了一系列的媒体,如叠氮血琼脂基地、哥伦比亚C.N.A琼脂基地等。

harlan teklad官网动物饲料代理商 强力霉素 多西环素 TD.01306 TD.05125 Doxycycline diets

harlan teklad官网动物饲料代理商 强力霉素 多西环素 TD.01306 TD.05125

多西环素饮食

EnvigoTeclad饮食使各种多西环素包含饮食为您的Tet调节系统。可以添加一系列的多西环素(如强力霉素)。典型的包含率是200毫克/千克和625毫克/千克,但一些研究人员指定一个更高或更低的水平。

饮食是很容易定制的,因为他们是新鲜的,当订购。我们目前有超过150个不同的强力霉素配方组合。我们可能有一个现有的产品编号,以满足您的规格。规格包括:基础饮食,多西环素浓度和食用色素。联系我们如果你在下面找不到合适的选择的话,来讨论你的需求。

全球饮食基础
产品编号 基础饮食 强力霉素透明
每公斤饲料毫克
每日强力霉素
3-5克日粮中的毫克
替代
食用色素
TD.01306
备好
2018 625 1.6 – 2.7 TD.08541红色
TD.120769蓝色
TD.00502 2018 200 0.5 – 0.9 TD.04104绿色
TD.110720 2020 625 1.6 – 2.7 TD.130141红色
TD.09651 2019 625 1.6 – 2.7 TD.09761绿色
TD.02503 2016 625 1.6 – 2.7 TD.140263蓝色
TD.00426 2014 625 1.6 – 2.7 TD.07382红色
传统饮食基础
产品编号 基础饮食 强力霉素透明
每公斤饲料毫克
每日强力霉素
3-5克日粮中的毫克
替代
食用色素
TD.05125 7012 625 1.6 – 2.7 TD.08434蓝色
TD.98186 7012 200 0.5 – 0.9 红色

与给水相比,饮食分娩是许多研究人员的一个更好的选择。

  • 饮食能保护身体免受光线伤害。水可能必须用深色或铝箔包装的瓶子浇水。
  • 饮食通常每周改变一次。水可能需要每隔几天更换一次。
  • 饮食供应也可以减少脱水的风险,并避免需要给予蔗糖(考索恩等)。艾尔。(2007年)

含有多西环素的饮食经常以辐照形式订购。辐照必须在订购时要求,并将增加大约两周的准备时间。

如果你的工作需要不含苜蓿的食物进行荧光成像,可以考虑使用全球啮齿动物的饮食基础。如果需要进一步的成像清晰度,我们可以用多西环素进行纯化饮食。

联系我们根据您的具体需求,我们可以推荐一个现有的产品代码或创建一个新的配方。

Doxycycline diets | Envigo

Envigo Teklad diets makes a variety of doxycycline containing diets for your Tet regulated systems. A range of levels of doxycycline (as doxycycline hyclate) can be added. Typical inclusion rates are 200 and 625 mg/kg diet, but some researchers specify a higher or lower level.

Diets are easily customizable as they are made fresh when ordered. We currently have over 150 different doxycycline formula combinations. We likely have an existing product number to meet your specifications. Specifications include: base diet, concentration of doxycycline, and food coloring.

Global diet base
Product number Base diet Doxycycline hyclate
mg per kg diet
Daily doxycycline
mg in 3-5 g diet
Alternative
with food coloring
TD.01306
stocked
2018 625 1.6 – 2.7 TD.08541Red
TD.120769Blue
TD.00502 2018 200 0.5 – 0.9 TD.04104Green
TD.110720 2020 625 1.6 – 2.7 TD.130141Red
TD.09651 2019 625 1.6 – 2.7 TD.09761Green
TD.02503 2016 625 1.6 – 2.7 TD.140263Blue
TD.00426 2014 625 1.6 – 2.7 TD.07382Red
Traditional diet base
Product number Base diet Doxycycline hyclate
mg per kg diet
Daily doxycycline
mg in 3-5 g diet
Alternative
with food coloring
TD.05125 7012 625 1.6 – 2.7 TD.08434Blue
TD.98186 7012 200 0.5 – 0.9 Red

Compared to water delivery, diet delivery is a preferable option for many researchers.

  • Diet offers protection from light. Water may have to be given in dark-colored or foil-wrapped bottles
  • Diet is typically changed once per week. Water may need to be changed every few days
  • Diet delivery may also reduce risk of dehydration and preclude the need to give with sucrose (Cawthorne et. al. 2007)

Doxycycline containing diets are often ordered in irradiated form. Irradiation must be requested at the time of ordering and will add approximately two weeks to the lead time.

If your work requires an alfalfa-free diet for fluorescent imaging, consider using a global rodent diet base. If further imaging clarity is needed, we can make purified diets with doxycycline.

 

Harlan teklad官网动物饲料 Rodent diets 啮齿动物饮食

Harlan teklad官网动物饲料 Rodent diets 啮齿动物饮食

作为一名研究人员,你想要有尽可能多的控制进入你的研究动物。在恩维戈,我们理解。这就是为什么我们开发了特克拉德全球啮齿动物饮食®.

特克拉德全球啮齿动物饮食®是一个特殊的综合素食实验室啮齿动物的饮食发展为营养完整的各个生命阶段,从繁殖到长期维持。全球啮齿动物实验室饮食中含有更适合现代生物医学研究需要的蛋白质、能量、维生素和矿物质水平。

此外,在全球啮齿类饮食中,人们特别注意尽可能避免使用据报对实验结果产生不利影响的成分。这导致了一系列特克拉德啮齿动物实验室饮食,其中包括:

  • 无鱼粉
  • 无肉食或肉类副产品
  • 无苜蓿粉
  • 不含豆粕或降低水平
  • 无动物脂肪

通过排除动物副产品,避免了亚硝胺(一种潜在的致癌物)的存在.紫花苜蓿粉的排除降低了叶绿素,提高光学成像清晰度。减少或去除豆粕,加上消除紫花苜蓿粉,可使自然产生的植物雌激素水平降至最低。植物雌激素与内源性雌激素相互作用,可能对许多研究产生影响。研究领域。在以下几篇文章中可以了解更多关于这一点的内容:

产品
特克勒德啮齿类食物 不可蒸压式 高压釜 辐照
总蛋白14% 2014年c 2014年s 2914
总蛋白16% 2016年c 2016年s 2916
Teklead全局18%蛋白 2018年c 2018S,2018SX 2918
TKLAD全局19%蛋白挤出 2019 2019 S 2919
全无大豆蛋白挤出 2020 X 2020 SX 2920 X
传统饮食 见更多
并不是所有的产品都是在当地库存的,可能需要延长交货期和额外的费用。
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。
折叠所有标签

传统的啮齿动物饮食是在几十年前根据对啮齿动物的营养、成分和当时的饮食制造的理解而制定的。虽然传统的饮食将提供已知的您的实验室动物的营养需求,我们建议您考虑使用我们的新的全球饮食线的饮食,以满足您的现代研究需要。

特克拉德全球啮齿动物饮食®现代公式旨在减少研究变量。具体来说,这些饮食含有更合适的营养水平,限制或排除据报道对各种研究终点有影响的成分。

  • 更低、更合适的蛋白质水平可以提高存活率和降低发病率。
  • 不含亚硝胺的素食(一种潜在的致癌物)
  • 除紫花苜蓿粉外,可大大提高荧光成像清晰度。
  • 用来排除或降低豆粕,从而减少异黄酮的存在。异黄酮是实验室动物饮食中发现的植物雌激素的主要类型。
  • 挤压后的啮齿类食物能显着地减少压蒸后的结块和硬度。2018SX2019 S2020 SX),并且通常导致更少的饮食垃圾和更干净的笼子

特克勒德啮齿动物饮食是一种特殊的天然成分饮食,旨在提供所有已知营养的适当平衡,这些营养素被认为对老鼠、沙土鼠和仓鼠的生长、维持和繁殖至关重要。这些饮食符合国家研究委员会对啮齿类动物的营养要求(1995年)。

特克拉德啮齿动物的饮食提供了统一的营养。它们是一种固定的配方奶饮食,旨在尽量减少营养差异,否则,如果一种饮食的成分组成从一批改变到下一批,就会发生这种变化。

蛋白质主要由植物来源提供。补充氨基酸是为了提供适当的数量和平衡的必需氨基酸。所有啮齿动物的饮食都含有维生素和矿物质,以帮助支持体液的调节和身体系统的正常运作,以确保研究鼠的充分生长、维持和繁殖。可蒸压饮食补充维生素,以弥补在高压灭菌过程中发生的损失。由于我们的饮食是营养完整和平衡的,所以没有必要添加膳食补充剂。

没有一个确定的点,人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲,当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月,有时甚至在生产后12个月。这种实践经验,随着时间的推移,再加上文献支持和维生素测试,让我们相信,这些饮食继续支持动物的健康和研究的完整性,至少在9个月后生产。如果你不确定当地的政策,请向你的机构寻求指导。

建议的储存条件:

  • 凉爽和干燥;在华氏70度或以下,湿度最好在50%以下,但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中,防止连续暴露于光线下,并将空气暴露在最小范围内。

标准的天然成分啮齿类食物是大鼠、老鼠、沙土鼠和仓鼠的完整饮食,这是应该允许的。[医]锂节食的机会。任何时候都应该有淡水供应。

As a researcher, you want to have as much control as possible over what goes into your study animals. At Envigo, we understand that. That is why we developed Teklad Global Rodent Diets®.

Teklad Global Rodent Diets® are a special integrated range of vegetarian laboratory rodent diets developed to be nutritionally complete for various life stages from breeding through long-term maintenance. Global rodent laboratory diets contain levels of protein, energy, vitamins and minerals that are more appropriate to the needs of modern biomedical research studies.

Furthermore, in global rodent diets particular attention has been placed on avoiding, as far as practical, ingredients that are reported to have adverse confounding effects on experimental results. This has resulted in a range of Teklad rodent laboratory diets that contain:

  • No fish meal
  • No meat meals or meat by-products
  • No alfalfa meal
  • No soybean meal or reduced levels
  • No animal fat

By excluding animal by-products, the presence of nitrosamines (a potential carcinogen) is avoided. Exclusion of alfalfa meal reduces chlorophyll, improving optical imaging clarity. Reduction or removal of soybean meal, together with elimination of alfalfa meal, minimizes levels of naturally-occurring phytoestrogens. Phytoestrogens interact with endogenous estrogens and potentially can affect studies in many research areas. Read more about this in these pieces:

Products
Teklad rodent diets Non-autoclavable form Autoclavable Irradiated
Teklad global 14% protein 2014, 2014C 2014S 2914
Teklad global 16% protein 2016, 2016C 2016S 2916
Teklad global 18% protein 2018, 2018C 2018S, 2018SX 2918
Teklad global 19% protein extruded 2019 2019S 2919
Teklad global soy protein-free extruded 2020X 2020SX 2920X
Traditional diets see more
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

COLLAPSE ALL TABS

Traditional rodent diets were formulated decades ago based on understanding of rodent nutrition, ingredients, and diet manufacturing at the time. While traditional diets will supply the known nutrient needs of your laboratory animals, we recommend you consider the use of a diet from our newer global diet line for your modern research needs.

Teklad Global Rodent Diets® are modern formulas designed to reduce research variables. Specifically, these diets contain more appropriate nutrient levels, and limit or exclude ingredients that are reported to have effects on a wide variety of research endpoints.

  • Lower, more appropriate protein levels can improve survival and reduce morbidity
  • Vegetarian with no nitrosamines (a potential carcinogen)
  • Formulated to exclude alfalfa meal, greatly improving fluorescent imaging clarity
  • Formulated to exclude or lower soybean meal, thus minimizing the presence of isoflavones, the primary type of phytoestrogen found in lab animal diets
  • Extruded rodent diets dramatically reduce clumping and hardness after autoclaving (2018SX2019S2020SX), and in general result in less diet waste and cleaner cages

Teklad rodent diets are natural-ingredient diets specifically formulated to provide the proper balance of all known nutrients considered essential for the growth, maintenance, and reproduction of rats, mice, gerbils and hamsters. These diets conform to the nutrient requirements for rodents established by the National Research Council (1995).

Teklad rodent diets provide uniform nutrition. They are fixed-formula diets designed to minimize the nutrient variances which otherwise could occur if the ingredient composition of a diet were altered from one batch to the next.

Protein is supplied primarily by plant sources. Supplemental amino acids are added to provide the proper amount and balance of essential amino acids. All rodent diets are fortified with vitamins and minerals to help support the regulation of body fluids and the proper functioning of body systems to ensure the adequate growth, maintenance, and reproduction of research rodents. Autoclavable diets are supplemented with additional vitamins to compensate for losses that occur during autoclaving. Since our diets are nutritionally complete and balanced, it is not necessary to add dietary supplements.

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.

Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit with humidity ideally below 50%, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

Standard natural ingredient rodent diets are complete diets for rats, mice, gerbils and hamsters, that should be allowed ad libitum access to the diet. Fresh water should be available at all times.

harlan teklad官网动物饲料代理商 药物饮食 TD.130755伊维菌素 TD.01432芬苯达唑

harlan teklad官网动物饲料代理商 药物饮食 TD.130755伊维菌素 TD.01432芬苯达唑

药物饮食

特克拉德药物实验室动物饮食是在一个附属工厂或在我们的定制研究饮食设施生产。与客户服务部门或当地Envigo客户代表联系,了解库存饮食的定价和供应情况。联系营养师讨论这些或其他药物饮食的定制版本。

药物饮食必须按照兽医的指示使用。

含药啮齿动物饲料
主要目的 产品代码 药物治疗 浓度 基础饮食 包装
毛螨处理 TD.130755 伊维菌素 百万分之十二 2018 25磅包-辐照
粉螨治疗 TD.01432 芬苯达唑 百万分之150 2008 S 25磅包-辐照*
50磅包-高压釜
肺孢子虫p肺炎
预防
TD.06596 Uniprim® 275 ppm甲氧苄啶
1365 ppm磺胺嘧啶
2018 25磅包-辐照*

伊维菌素定制饮食®,芬苯达唑是可行的。修改包括:不同的基础饮食,染色与食物染料,以及其他剂量的浓度,根据您的独特要求。联系营养师来讨论你的需求。

其他药物和化合物,如强力霉素他莫昔芬可以添加到我们的定制研究饮食设施的饮食。访问我们的定制研究饮食网站或联系我们以获得更多信息。

Medicated diets | Envigo

Teklad medicated lab animal diets are manufactured either at a subsidiary plant or at our custom research diet facility. Contact customer service or your local Envigo account representative for pricing and availability of stocked diets. Contact a nutritionist to discuss customized versions of these or other medicated diets.

Medicated diets must be used as directed by a veterinarian.

Stocked medicated rodent diets
Primary Purpose Product Code Medication Concentration Base diet Packaging
Fur mite treatment TD.130755 Ivermectin 12 ppm 2018 25 lb bag- irradiated
Pinworm treatment TD.01432 Fenbendazole 150 ppm 2018S 25 lb bag- irradiated*
50 lb bag- autoclavable
Pneumocystis pneumonia
prevention
TD.06596 Uniprim® 275 ppm trimethoprim
1365 ppm sulfadiazine
2018 25 lb bag- irradiated*

Custom diets with Ivermectin, Uniprim®, and Fenbendazole are available. Modifications include: different base diet, coloring with food dyes, and other dosing concentrations based on your unique requirements. Contact a nutritionist to discuss your needs.

Other medications and compounds such as doxycycline and tamoxifen may be added to diets at our custom research diet facility. Visit our custom research diets site or contact us for additional information.

harlan teklad官网TD.02028 TD.02028 TD.96121 动物饲料 胆固醇和胆酸盐来源的纯化高脂饮食


harlan teklad官网TD.02028 TD.02028 TD.96121 动物饲料 胆固醇和胆酸盐来源的纯化高脂饮食

野生型小鼠和大鼠一般对动脉粥样硬化有抵抗力,需要更极端的饮食操作来改变脂蛋白谱,形成轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。现代配方完全是由纯化成分制成的,因为据报道,这种更精细的方法可以减少较少精制和较传统饮食方法引起的胆结石和肝脏损害的发生率。为了在野生型动物中诱导轻度动脉粥样硬化,可对“西方”纯化饲料进行改良,以提高胆固醇(1-1.25%),并添加胆酸钠或胆酸等胆盐。联系我们获得更多的信息,修改,或可能的控制饮食。

添加胆固醇和胆酸盐来源的纯化高脂饮食的例子*:

  • TD.0202821%乳脂(1.25%胆固醇,0.5%胆酸)
  • TD.0923715%乳脂饮食(1%胆固醇,0.5%胆酸钠)

添加胆固醇的纯化高脂饮食的例子(没有胆酸来源):

研究用途:

主要在野生型小鼠和大鼠诱发高胆固醇血症和轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。

不会助长肥胖。

主要饮食特征:

  • 高脂饮食(体重15-20%;脂肪34-45千卡)
  • 饱和脂肪酸(SFA>总脂肪酸的55%)
  • 乳脂/黄油、可可脂
  • 蔗糖(重量占30%-50%)
  • 胆固醇(1-1.25%)
  • 巧克力源(0.5%)*

参考资料:

  1. 番茄汁番茄红素对大鼠肝脏脂肪变性的影响。j Nutr Biochem,2013年。24(11):P。1870-81
  2. 高,Q,等,动脉粥样硬化饮食加剧了小鼠缺乏谷胱甘肽过氧化物酶结肠炎。炎症肠Dis,2010年。16(12):P。2043-54
  3. Lichtman,A.H.,等,高脂血症和动脉粥样硬化病变的发展,低密度脂蛋白受体缺乏的小鼠,喂食定义半纯化饮食与不含胆酸。Arteroscler Thromb VASc Biol,1999年。19(8):P。1938-44年。
  4. 慢性精神应激和致动脉粥样硬化饮食对小鼠主动脉免疫炎症环境的影响。BrainBehav Immun,2011年。25(8):P。1649-57
  5. Nishina,P.m.,等,动物和植物来源的饮食脂肪对C57BL/6J小鼠因饮食引起的脂肪条纹损害的影响。j Lipid RES,1993年。34(8):P。1413-22
  6. Nishina,P.m.,等,9种近交系小鼠动脉粥样硬化及血浆和肝脏脂质。脂质,1993年。28(7):P。599-605
  7. 月,P,等,增强CD 36空小鼠肝脏载脂蛋白A-I分泌及胆固醇和磷脂的外周流出。PLOS One,2010年。5(3):P。E 9906
  8. Nishina,下午,J.Verstuyft,B.Paigen,合成低脂和高脂肪饮食,用于研究小鼠动脉粥样硬化。j Lipid RES,1990年。31(5):P。859-69

*胆酸钠或胆酸有助胆固醇和脂肪的吸收,并可透过胆汁酸合成减少胆固醇的排出。然而,如果你的研究不想包括胆酸盐的来源,没有胆酸盐的饮食是可用的。看见TD.96121为了纯正的饮食TD.94059混合饮食。请与我们联系,了解其他选项。

Wild type mice and rats generally are resistant to atherosclerosis, requiring more extreme dietary manipulation to modify lipoprotein profiles and develop mild atherosclerosis (foam cells, fatty streaks). Modern formulations are made completely of purified ingredients because this more refined approach has been reported to decrease the incidence of gallstones and liver damage associated with less refined and more traditional dietary approaches. To induce mild atherosclerosis in wild type animals, the “Western” purified diet can be modified to increase cholesterol (1-1.25%) and add a bile salt such as sodium cholate or cholic acid. Contact us for more information, modifications, or possible control diets.

Examples of purified high fat diets with added cholesterol and cholate source*:

  • TD.02028    21% milkfat (1.25% cholesterol, 0.5% cholic acid)
  • TD.09237    15% milkfat diet (1% cholesterol, 0.5% sodium cholate)

Examples of purified high fat diets with added cholesterol (without cholate source):

  • TD.96121    21% milkfat (1.25% cholesterol)

Research Use:

Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) primarily in wild type mice and rats.

Will not promote obesity.

Key dietary features:

  • High fat diet (15-20% by weight; 34 – 45% kcal from fat)
  • Saturated fatty acids (SFA >55% of total fatty acids)
  • Milkfat/butterfat, cocoa butter
  • Sucrose (30-50% by weight)
  • Cholesterol (1 – 1.25%)
  • Cholate source (0.5%)*

References:

  1. Bernal, C., et al., Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis. J Nutr Biochem, 2013. 24(11): p. 1870-81.
  2. Gao, Q., et al., Atherogenic diets exacerbate colitis in mice deficient in glutathione peroxidase. Inflamm Bowel Dis, 2010. 16(12): p. 2043-54.
  3. Lichtman, A.H., et al., Hyperlipidemia and atherosclerotic lesion development in LDL receptor-deficient mice fed defined semipurified diets with and without cholate. Arterioscler Thromb Vasc Biol, 1999. 19(8): p. 1938-44.
  4. Marcondes, M.C., et al., Effects of chronic mental stress and atherogenic diet on the immune inflammatory environment in mouse aorta. Brain Behav Immun, 2011. 25(8): p. 1649-57.
  5. Nishina, P.M., et al., Effects of dietary fats from animal and plant sources on diet-induced fatty streak lesions in C57BL/6J mice. J Lipid Res, 1993. 34(8): p. 1413-22.
  6. Nishina, P.M., et al., Atherosclerosis and plasma and liver lipids in nine inbred strains of mice. Lipids, 1993. 28(7): p. 599-605.
  7. Yue, P., et al., Enhanced hepatic apoA-I secretion and peripheral efflux of cholesterol and phospholipid in CD36 null mice. PLoS One, 2010. 5(3): p. e9906.
  8. Nishina, P.M., J. Verstuyft, and B. Paigen, Synthetic low and high fat diets for the study of atherosclerosis in the mouse. J Lipid Res, 1990. 31(5): p. 859-69.

*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis. However, if including a cholate source is not desired for your research, diets without cholate are available. See TD.96121 for a purified diet and TD.94059 for a hybrid diet. Contact us for additional options.

Harlan teklad官网动物饲料 Guinea pig diets 豚鼠饮食 上海动物饲料定制

Harlan teklad官网动物饲料 Guinea pig diets 豚鼠饮食 上海动物饲料定制

特克勒德豚鼠饮食是为了满足豚鼠在生命周期的各个阶段的营养需要而制定的完整和平衡的饮食。

植物和鱼粉来源所提供的蛋白质提供了豚鼠所需必需氨基酸的平衡。大豆油中的脂肪提供了良好的毛发所必需的脂肪酸。

特克拉德豚鼠的饮食适当强化维生素和矿物质,以满足豚鼠在生长、维持和繁殖过程中的需要。

维生素C被包括在这些饮食中,因为豚鼠(就像人类和其他灵长类动物一样)需要饮食中的维生素C来防止坏血病。稳定维生素C(L-抗坏血酸-2-聚磷酸)用于延长保质期.

紫花苜蓿粉是一种高品质的饲料产品,有助于维持豚鼠消化系统的正常运转。该公司,颗粒饮食有助于防止饲料浪费。

产品
特克乐豚鼠饲料 不可蒸压式 辐照
全球豚鼠饮食 2040,2040 C 2940
全球高纤维豚鼠饮食 2041 2941
特克乐豚鼠饲料 7006
并不是所有的产品都是在当地库存的,可能需要延长交货期和额外的费用。
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。
折叠所有标签

没有一个确定的点,人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲,当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月,有时甚至在生产后12个月。这种实践经验,随着时间的推移,再加上文献支持和维生素测试,让我们相信,这些饮食继续支持动物的健康和研究的完整性,至少在9个月后生产。如果你不确定当地的政策,请向你的机构寻求指导。

建议的储存条件:

  • 凉爽和干燥;在华氏70度或以下,湿度低于50%的理想值,但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中,防止连续暴露于光线下,并将空气暴露在最小范围内。

应该允许几内亚猪[医]锂获得放置在笼的前部或侧面的喂食器中的食物。

Teklad guinea pig diets are complete and balanced diets formulated to meet the nutritional needs of guinea pigs during various stages of the life cycle.

Protein supplied by plant and fish meal sources provides the balance of essential amino acids required by guinea pigs. Fat from soybean oil supplies essential fatty acids necessary for a good hair coat.

Teklad guinea pig diets are properly fortified with vitamins and minerals to meet the needs of guinea pigs during growth, maintenance, and reproduction.

Vitamin C is included in these diets because guinea pigs (as do man and other primates) require a dietary source of vitamin C to prevent scurvy. Stabilized vitamin C (L-ascorbyl-2-polyphosphate) is used to extend the shelf life.

Alfalfa meal is included as a high-quality forage product to help maintain the normal functioning of the guinea pig’s digestive system. The firm, pelleted diet aids in preventing feed wastage.

Products
Teklad guinea pig diets Non-autoclavable form Irradiated
Teklad global guinea pig diet 2040, 2040C 2940
Teklad global high fiber guinea pig diet 2041 2941
Teklad guinea pig diet 7006
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

COLLAPSE ALL TABS

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.

Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit, humidity below 50% ideal, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

Guinea pigs should be allowed ad libitum access to diets placed in a feeder attached to the front or side of the cage.

Harlan teklad官网动物饲料 Rabbit diets 兔饲料 国内高纤维兔饲料定制

Harlan teklad官网动物饲料 Rabbit diets 兔饲料 全球高纤维兔饲料

特克勒德兔饲料是营养完整的颗粒饲料制定,以满足已知的营养需求兔在生长,繁殖和维持。

高质量的植物蛋白质来源提供了适当数量和比例的必需氨基酸,以促进家兔的一般健康和状况,在所有阶段的生命周期。

特克拉德兔日粮中含有脱水苜蓿粉,这是一种高品质的饲料成分,能促进消化系统的正常运转。紫花苜蓿粉中的蛋白质也被兔很好地利用。

矿物质和维生素强化这些饮食确保充足的营养平衡,以促进适当的生长,发育,维持和繁殖的研究兔。

产品
特克乐兔饲料 不可蒸压口罩 辐照
全兔饮食 2030,2030 C 2930
全球高纤维兔饲料 2031,2031 C 2931
15%兔饲料 8630
并不是所有的产品都是在当地库存的,可能需要延长交货期和额外的费用。
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。
折叠所有标签

没有一个确定的点,人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲,当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月,有时甚至在生产后12个月。这种实践经验,随着时间的推移,再加上文献支持和维生素测试,让我们相信,这些饮食继续支持动物的健康和研究的完整性,至少在9个月后生产。如果你不确定当地的政策,请向你的机构寻求指导。

建议的储存条件:

  • 凉爽和干燥;在华氏70度或以下,湿度最好在50%以下,但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中,防止连续暴露于光线下,并将空气暴露在最小范围内。

兔子可能会被限制喂食,把一定数量的饲料放在鳄鱼或饲料斗一天一次。在维持和妊娠期限制喂养是一种有效的方法,以满足兔的营养需求,但它防止过多的体重增加。兔子也可以自食其力,把饲料放在料斗里,它们可以随意进食。该方法对兔生长、泌乳和幼仔繁殖最有效。

兔子的摄食要求会随品种、年龄和大小而变化。通过观察和控制喂养,可以保持适当的身体状况,以达到最大的性能。一只10磅重的新西兰白兔每天将消耗大约150克特克勒德兔的食物。

Teklad rabbit diets are nutritionally complete pelleted diets formulated to meet the known nutrient requirements of the rabbit during growth, reproduction and maintenance.

High-quality plant protein sources supply the proper amounts and proportions of essential amino acids necessary to promote the general health and condition of rabbits during all phases of the life cycle.

Teklad rabbit diets contain dehydrated alfalfa meal, a high-quality forage ingredient that promotes the proper functioning of the digestive system. The protein in alfalfa meal also is utilized well by rabbits.

Mineral and vitamin fortification of these diets ensures an adequate nutritional balance to promote the proper growth, development, maintenance, and reproduction of research rabbits.

Products
Teklad rabbit diets Non-autoclavable orm Irradiated
Teklad global rabbit diet 2030, 2030C 2930
Teklad global high fiber rabbit diet 2031, 2031C 2931
Teklad 15% rabbit diet 8630
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

COLLAPSE ALL TABS

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.

Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit with humidity ideally below 50%, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

Rabbits may be limit-fed by placing a certain amount of feed in crocks or feeding hoppers once a day. Limit-feeding during maintenance and gestation is an efficient method of meeting the nutritional needs of the rabbit, yet it prevents excess weight gain. Rabbits also may be self-fed by placing feed in a hopper where they may eat at will. This method is most efficient for growing rabbits, lactating does, and young breeding stock.

Rabbit feeding requirements will vary with rabbit breed, age, and size. Through observation and controlled feeding, the proper body condition can be maintained for maximum performance. A ten-pound New Zealand white rabbit will consume approximately 150 g of Teklad rabbit diet per day.

harlan Teklad diet, bedding and enrichment 饮食、垫料和营养丰富动物饲料

harlan Teklad diet, bedding and enrichment 饮食、垫料和营养丰富动物饲料

饮食、垫料和营养丰富

你的研究成果在很大程度上取决于你的研究模型是什么。确保你的研究动物有最适当的饮食是保持一致,可靠的研究数据的关键。你是否需要一个标准啮齿动物饮食或者是定制研究饮食,我们知道如何提供健全的营养解决方案。

依靠我们对你的研究和动物福利的承诺来保护你工作的潜力。了解Envigo实验室动物饮食如何帮助您提高您的研究:

通过提供全方位的实验动物饮食,床上用品和丰富,Envigo作为您的研究需求的一站式供应商。

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各种实验室动物的标准天然成分饮食由谷物、植物和动物蛋白质等农产品组成。这些食物被用来满足动物群体在繁殖、生长和维持方面的日常需要。如果仔细选择,它们也可以支持许多研究目标。

所有特克拉德标准天然配料饮食的特点是我们的固定配方理念,加上严格的配料采购实践,然后是自动化和受控的生产实践。常规的,可蒸压的,认证的,和辐照实验日粮是众多选择之一。

了解更多关于标准天然成分饮食的知识

如果你需要控制营养,诱发疾病或提供特定剂量的饮食,你可以利用我们的经验,净化或其他类型的定制研究饮食。我们的营养学家可以与您独特的规格,以找到一个符合您的研究要求的特克乐解决方案。

了解更多关于定制研究饮食的信息

为了治疗一种疾病或预防疾病或暴发,使用由兽医指导的特克勒德药物饮食可以支持储存的药物饮食。定制饮食与各种药物或化合物也可以添加在我们的定制研究饮食设施的要求。

What comes out of your research depends in large part on what goes into your research models. Ensuring your study animals have the most appropriate diet is critical to maintaining consistent, reliable research data. Whether you need a standard rodent diet or a custom research diet, we know how to provide sound nutrition solutions.

Protect the potential of your work by relying on our commitment to your research and animal welfare. Learn how Envigo laboratory animal diets can help advance your studies with:

By providing a full range of lab animal diets, bedding and enrichment, Envigo serves as your one-stop supplier for your research needs.

COLLAPSE ALL TABS

Standard natural ingredient diets for a variety of laboratory animal species are comprised of agricultural commodities such as grains, and plant and animal proteins. These diets are used to meet the everyday needs of animal colonies for breeding, growth and maintenance. When carefully chosen, they also can support many research objectives.

The hallmark of all Teklad standard natural ingredient diets is our fixed formulation philosophy coupled with stringent ingredient procurement practices, followed by automated and controlled manufacturing practices. Regular, autoclavable, certified, and irradiated laboratory diets are among the many options.

Learn more about standard natural ingredient diets

If you need to control nutrients, induce disease or provide specific doses through a diet, you can leverage our experience with purified or other types of custom research diets. Our nutritionists can work with your unique specifications to find a Teklad solution that meets your study’s requirements.

Learn more about custom research diets

For treatment of a condition or to prevent illness or outbreak, the use of Teklad medicated diets as directed by a veterinarian can be supported by stocked medicated diets. Custom diets with various medications or compounds can also be added by request at our custom research diet facility.

Learn more about medicated diets

Harlan teklad官网动物饲料代理商 猫 雪貂 反刍动物 国内动物饲料定制

Harlan teklad官网动物饲料代理商 猫 雪貂 反刍动物 国内动物饲料定制

 

特克拉德全球猫粮(2060)是专门用来提供所有已知营养的适当平衡,被认为对研究猫的生长、维持和繁殖是必不可少的。

该饮食提供统一的营养,是一种固定的配方饮食设计,以尽量减少营养差异,否则可能会发生,如果饮食的成分组成从一批改变到下一批。与其他猫粮不同,它不含肉类替代品、人工调味品、过量谷物、化学色素或填充物。

猫有不寻常的营养需求。它们不能有效地将色氨酸转化为烟酸,不能将β胡萝卜素转化为维生素A,也不能去饱和亚油酸。它们需要高水平的蛋白质,而氨基酸牛磺酸是防止眼部损害和扩张性心肌病。特克拉德全球猫粮是为了满足这些特殊需要而设计的。此外,它的配方是低镁和低灰分,高肉类蛋白质,以产生酸性尿液,这降低了猫尿综合征的风险。

喂食方向

特克勒德全球猫饮食是一个完整的饮食为猫和小猫。[医]锂在任何时候都应提供获得饮食的机会。猫通常一天只吃一小部分食物,而且他们有一种正常的倾向,即只吃少量的水。每种动物都应该有淡水。

产品
特克拉德猫粮 不可蒸压式
特克拉德全球猫粮 2060,2060 C
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。

特克拉德全球雪貂饲料(2072)专为提供对研究雪貂的生长、维持和繁殖所必需的所有已知营养物的适当平衡而制定的。

雪貂实验室饮食提供统一的营养,是一种固定的配方饮食设计,以尽量减少营养变化,否则可能会发生如果饲料的成分组成从一批改变到下一批。

雪貂是一种特殊的食肉动物,肠道很短。人们认为,像猫一样,雪貂不能去饱和亚油酸。由于这些原因,一般建议雪貂日粮中含有大量的动物蛋白质和脂肪。在饮食中添加氨基酸牛磺酸是预防眼部损害和扩张型心肌病的一种安全措施。特克拉德全球雪貂饮食旨在满足这些特殊需要,包括大量的家禽副产品膳食和家禽脂肪。此外,它的配方是低镁和低灰分,这减少了泌尿疾病的风险。不像低质量的雪貂饲料,它不包含肉类替代品,人工调味品,谷物,化学色素,或填料。

喂食方向

特克拉德全球雪貂的饮食是一个完整的饮食Jills,和圣基茨。提供[医]锂在自食其力者中获得饮食的机会。雪貂通常一天只吃一小部分食物,而且他们有一种正常的倾向,即只消耗少量的水。雪貂在任何时候都能很容易地获得新鲜和清洁的食物和水,这一点至关重要。

产品
雪貂饲料 不可蒸压式
特克拉德全球雪貂饲料 2072,2072C
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。

反刍动物饮食(7060)是专门为各种实验室反刍动物提供所有已知营养的适当平衡。该饮食提供统一的营养,是一种固定配方的饮食设计,以尽量减少营养差异,否则可能会发生如果饮食成分组成改变从一批到下一批。

反刍动物需要大量纤维以保持瘤胃健康。绵羊需要铜,但对铜的毒性也很敏感。反刍动物日粮中含有丰富的纤维,支持微生物发酵,维持瘤胃功能。该日粮铜含量低,容易超过大多数反刍动物对铜的要求,同时避免了铜对绵羊的毒性。

喂食方向

特克拉德反刍动物的饮食是一个完整的饮食,为各种实验室反刍动物品种,一般应该每天以2%至3%的体重,取决于期望的增长率。淡水应该总是提供给每种动物,特别是在温暖的夏天。

产品
反刍动物饲料 不可蒸压式
反刍动物饮食 7060、7060 C
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。

没有一个确定的点,人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。九个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲,当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月,有时甚至在生产后12个月。这种实践经验,随着时间的推移,再加上文献支持和维生素测试,让我们相信,这些饮食继续支持动物的健康和研究的完整性,至少在9个月后生产。如果你不确定当地的政策,请向你的机构寻求指导。

建议的储存条件:

  • 凉爽和干燥;在华氏70度或以下,湿度低于50%的理想值,但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中,防止连续暴露于光线下,并将空气暴露在最小范围内。

Envigo also manufactures and stocks diets for less commonly used laboratory animals including cats, ferrets, and for ruminants such as sheep, goats and cows.

COLLAPSE ALL TABS

Teklad global cat diet (2060) is specifically formulated to provide the proper balance of all known nutrients considered essential for growth, maintenance, and reproduction of research cats.

The diet provides uniform nutrition and is a fixed-formula diet designed to minimize the nutrient variances that otherwise could occur if the ingredient composition of a diet were altered from one batch to the next. Unlike other cat foods, it does not contain meat substitutes, artificial flavorings, excessive grains, chemical colorings, or fillers.

Cats have unusual nutritional requirements. They cannot convert tryptophan to niacin effectively, cannot convert beta carotene to vitamin A, and cannot desaturate linoleic acid. They require an elevated level of protein, and the amino acid taurine is needed to prevent ocular lesions and dilated cardiomyopathy. Teklad global cat diet is designed to meet these special needs. In addition, it is formulated to be low in magnesium and ash, and high in meat protein to produce an acidic urine, which reduces the risk of feline urinary syndrome.

Feeding directions

Teklad global cat diet is a complete diet for cats and kittens. Ad libitum access to diet should be provided at all times. Cats normally consume small portions of food throughout the day, and they have a normal propensity to consume minimal amounts of water. Fresh water always should be available to each animal.

Products
Teklad cat diets Non-autoclavable form
Teklad global cat diet 2060, 2060C
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

Teklad global ferret diet (2072) is specifically formulated to provide the proper balance of all known nutrients considered essential for growth, maintenance, and reproduction of research ferrets.

The ferret laboratory diet provides uniform nutrition and is a Fixed Formula diet designed to minimize the nutrient variances that otherwise could occur if the ingredient composition of a diet were altered from one batch to the next.

Ferrets are obligate carnivores with a very short intestinal tract. It is assumed that like cats, ferrets cannot desaturate linoleic acid. For these reasons it is generally recommended that ferret diets contain high amounts of animal protein and fat. The amino acid taurine is supplemented in the diet as a safety measure against developing ocular lesions and dilated cardiomyopathy. Teklad global ferret diet is designed to meet these special needs by including a large amount of poultry by-product meal and poultry fat. In addition, it is formulated to be low in magnesium and ash, which reduces the risk of urinary disease. Unlike lower quality ferret diets, it does not contain meat substitutes, artificial flavorings, grains, chemical colorings, or fillers.

Feeding directions

Teklad global ferret diet is a complete diet for jills, and kitts. Provide ad libitum access to diet in a self-feeder. Ferrets normally consume small portions of food throughout the day, and they have a normal propensity to consume minimal amounts of water. It is crucial that fresh and clean food and water be kept easily accessible to ferrets at all times.

Products
Teklad ferret diets Non-autoclavable form
Teklad global ferret diet 2072, 2072C
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

Teklad ruminant diet (7060) is specifically formulated to provide the proper balance of all known nutrients to a variety of laboratory ruminant species. The diet provides uniform nutrition and is a fixed-formula diet designed to minimize the nutrient variances which otherwise could occur if the ingredient composition of a diet were altered from one batch to the next.

Ruminants require significant fiber to maintain proper rumen health. Sheep have a requirement for copper but are also very susceptible to copper toxicity. Teklad ruminant diet is high in fiber to support microbial fermentation and maintain proper rumen function. The diet has a low copper content easily exceeding the copper requirements of most ruminants while avoiding copper toxicity in sheep.

Feeding directions

Teklad ruminant diet is a complete diet for a variety of laboratory ruminant species and should generally be fed daily at two-to-three percent of body weight depending on the desired rate of gain. Fresh water always should be available to each animal particularly during warm summer days.

Products
Teklad ruminant diets Non-autoclavable Form
Teklad ruminant diet 7060, 7060C
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a nine month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.

Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit, humidity below 50% ideal, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

harlan teklad官网 TD.88051和TD.90221 TD.94059 胆固醇和胆酸盐的混合高脂饮食

Beverly Paigen and colleagues first characterized atherosclerosis development in C57BL/6 mice by feeding a hybrid atherogenic diet. The hybrid diet was created by mixing a natural ingredient mouse diet in a 3:1 ratio with a concentrated purified diet (containing 5% cholesterol and 2% sodium cholate; referred to as Thomas-Hartroft diet). The resulting mixture recreated in TD.88051/TD.90221 (same formula) contains ~15.8% fat, 1.25% cholesterol, and 0.5% sodium cholate. This group later compared the hybrid atherogenic diet approach to the more modern “western” purified atherogenic diet with added cholesterol and cholate and found that the hybrid atherogenic diet induced more gallstones and liver damage. Hybrid diets contain a variety of unrefined ingredients that may modify lipid metabolism and atherogenesis and do not allow for precise control of ingredients and nutrients for the study of chronic diseases. Although more refined diets have been developed, hybrid atherogenic diets are still popular for inducing mild atherosclerosis and gallstones in wild type mice and rats. Contact us for more information, modifications, or possible control diets.

Examples of hybrid high-fat diets with added cholesterol and cholate source*:

  • TD.88051 and TD.90221 (same formula) are Teklad product codes for hybrid atherogenic diets

Example of hybrid high-fat diet with added cholesterol (without cholate source):

Research Use:

Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) primarily in wild type mice and rats.

Will not promote obesity.

Also used for lithogenic (gallstone) rodent studies.

Key dietary features:

  • 75% rodent breeder diet; 25% purified ingredients
  • High fat (~15% by weight; 37% kcal from fat)
  • Saturated fatty acids (SFA >45% of total fatty acids)
  • Cholesterol (1.25%)
  • Cholate source (0.5%)*

References:

  1. Nishina, P.M., J. Verstuyft, and B. Paigen, Synthetic low and high fat diets for the study of atherosclerosis in the mouse. J Lipid Res, 1990. 31(5): p. 859-69.
  2. Clee, S.M., et al., Plasma and vessel wall lipoprotein lipase have different roles in atherosclerosis. J Lipid Res, 2000. 41(4): p. 521-31.
  3. George, J., et al., Enhanced fatty streak formation in C57BL/6J mice by immunization with heat shock protein-65. Arterioscler Thromb Vasc Biol, 1999. 19(3): p. 505-10.
  4. Miyake, J.H., et al., Transgenic expression of cholesterol-7-alpha-hydroxylase prevents atherosclerosis in C57BL/6J mice. Arterioscler Thromb Vasc Biol, 2002. 22(1): p. 121-6.
  5. Paigen, B., et al., Quantitative assessment of atherosclerotic lesions in mice. Atherosclerosis, 1987. 68(3): p. 231-40.
  6. Schreyer, S.A., D.L. Wilson, and R.C. LeBoeuf, C57BL/6 mice fed high fat diets as models for diabetes-accelerated atherosclerosis. Atherosclerosis, 1998. 136(1): p. 17-24.
  7. Vergnes, L., et al., Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression. J Biol Chem, 2003. 278(44): p. 42774-84.

*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis. However, if including a cholate source is not desired for your research, diets without cholate are available. See TD.96121 for a purified diet and TD.94059 for a hybrid diet. Contact us for additional options.

Harlan teklad官网动物饲料 Dog diets 狗的饮食饲料

Harlan teklad官网动物饲料 Dog diets 狗的饮食饲料

特克拉德狗的饮食是完整的固定配方饮食,旨在提供狗所需的所有基本营养,以实现有效的生长,维护和繁殖。补充膳食补充剂是不必要的。从几种饮食中选择最能满足你需要的食物。

特克拉德全球狗饮食是一个综合系列的蛋白质,脂肪和卡路里水平调整,以优化性能在特定的生命阶段。它们包括家禽副产品膳食,这是一种比传统肉类和骨粉更好的动物蛋白质来源。

动物和植物来源的蛋白质提供了必需氨基酸的适当平衡,以维持狗的整个生命周期的有效运作。高质量的动物脂肪是浓缩能量和必需脂肪酸的极好来源,以促进和支持研究犬、哺乳母犬和生长幼犬的一般状况。脂肪还能增强适口性。

特克拉德狗的饮食是加强适当的数量和平衡的维生素和矿物质,以帮助调节身体系统和体液,加强牙齿和骨骼,并保持良好的血液,皮肤和皮毛状况。这些饮食是为了帮助分解淀粉而挤压出来的。这就提高了消化率和适口性。

Teklad dog diets are complete fixed formula diets designed to provide all essential nutrients required by dogs to achieve efficient growth, maintenance and reproduction. Additional dietary supplements are unnecessary. Choose from several diets to best meet your needs.

Teklad global dog diets are an integrated series with protein, fat, and calories levels adjusted to optimize performance at specific life stages. They include poultry by-product meal, an improved source of animal protein over conventional meat and bone meals.

Protein from animal and plant sources provides the proper balance of essential amino acids to maintain efficient functioning of the dog’s body throughout its life cycle. High-quality animal fat is an excellent source of concentrated energy and essential fatty acids required to promote and support the general condition of research dogs, lactating bitches, and growing puppies. Fat also enhances palatability.

Teklad dog diets are fortified with the proper amounts and balance of vitamins and minerals required to help regulate body systems and fluids, strengthen teeth and bones, and maintain good blood, skin, and coat condition. The diets are extruded to help break down starches. This results in improved digestibility and palatability.

Products
Teklad dog diets Non-autoclavable form
Teklad global 21% protein dog diet 2021, 2021C
Teklad global 25% protein dog diet 2025, 2025C
Teklad global 27% protein dog diet 2027, 2027C
Teklad 21% lab dog diet 8755
Teklad 25% lab dog diet 86538727C
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

COLLAPSE ALL TABS

There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.

Recommended storage conditions:

  • Cool and dry; at or below 70 degrees Fahrenheit, humidity below 50% ideal, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

Teklad Dog Diets are designed to be fed to dogs under research conditions. Select the feeding method which keeps the animal in the proper body condition. The amount of food the research dog needs depends upon its size, age, breed, temperament, and amount of exercise.

Feed the pregnant female twice a day or ad libitum. Moisten the diet for her first few feedings after delivery. Thereafter, allow ad libitum access to diet and also feed her moistened food once a day.

Puppies will start eating diet (either moistened or dry) when they are about four weeks old. To encourage them to eat, add one cup water to each cup of dog food. Initially, feed the moistened food three times daily. The daily feedings (either dry or moistened) can be reduced to two as the puppies grow. The self-feeding program is ideal for puppies since they like to chew on dry food. They also can eat when they are hungry, assuring proper and adequate nutrition.

harlan teklad官网动物饲料配方表 TD.94047     AIN-93 vitamin mix TD.94049      AIN-93M mineral mix

饮食成分Envigo

harlan teklad官网动物饲料配方表 TD.94047     AIN-93 vitamin mix  TD.94049      AIN-93M mineral mix

你可能想要在你的研究地点或设施准备你自己的饮食,如果是这样的话,你取决于成分是最高的质量。Envigo可以为您提供许多相同的成分,用于生产我们先进的特克拉德定制研究饮食,以便您可以开发自己的配方。和往常一样,我们的营养专家在这里帮助您为您的配料和最终配方做出最佳决定。

我们的配料

我们提供几个配料供个人销售,以便您可以开发自己的混合。

“VFT”酪蛋白

  • “无维生素”测试酪蛋白(酒精提取)最适合于那些需要精确控制脂肪或维生素含量的纯正试验饮食配方。
  • VFT酪蛋白中许多维生素含量的降低使得它成为许多维生素研究的首选蛋白质来源。因此,“无维生素”的绰号是在许多年前给提取出来的酪蛋白起的。

维生素混合物

  • 以下常见的维生素混合物使用蔗糖或玉米淀粉作为载体。
  • 定制的维生素混合物可能使用纤维素,如果非营养载体是必要的。
  • 维生素混合物的制定考虑到了饮食中的包容率。多用或少用会损害你的实验动物的健康。
  • 对于那些自己准备饮食的人来说,维生素预混剂是向饮食中添加维生素的一种有效方法。
  • 维生素混合物应储存在4摄氏度或更低的接收。如果使用时间超过1个月,建议使用摄氏-20度。
  • 库存和定制维生素混合物的最低订购量为500克。
  • 我们可用的维生素混合物通常用于饮食,并可从库存中获得。
  • 维生素混合物在订购后几天内发货。

我们的公式示例

矿物混合物

  • 下面所示的常见矿物混合物是以蔗糖为载体的。
  • 如果需要非营养的载体,定制的矿物混合物可以使用纤维素,也可以不使用载体。
  • 我们的矿物质混合物是根据饮食包容率来制定的。多用或少用会损害动物的健康。
  • 对于那些自己准备饮食的人来说,矿物预混料是向饮食中添加矿物质的有效方法。
  • 矿物混合物应存放在干燥、凉爽的环境中,并在收到后一年内使用。库存和自定义矿物混合物的最低订购量为500克。
  • 这些矿物混合物通常用于饮食,并可从库存中获得。
  • 我们的矿物混合物在订货后几天内装运。

公式示例:

其他混合材料(可能从库存中获得,也可能无法从库存中获得):

  • TD.83171不含A,D,E,胆碱的维生素混合物
  • TD.81062基于AIN-76A的缺铁矿物配料
  • TD.79055AIN-76混合钙磷缺乏矿物
  • TD.98057AIN-93混合钙磷缺乏矿物
  • CA.170760罗杰斯-哈珀矿物混合物

Diet ingredients | Envigo

You may want to prepare your own diet at your research site or facility, and if that is the case, you depend on the ingredients being of the highest quality. Envigo can provide you with many of the same ingredients used to produce our advanced Teklad custom research diets so you can develop your own formula. And as always, our nutritional experts are here to help you make the best decisions for your ingredients and ultimate formulation.

Our ingredients

We offer several ingredients for individual sale so that you can develop your own blends.

“VFT” casein

  • “Vitamin-free” test casein (alcohol-extracted) is best suited for purified test diet formulas where fat or vitamin content needs to be precisely controlled
  • The reduced levels of many vitamins in VFT casein make it the preferred protein source for many vitamin studies. Thus, the nickname “Vitamin-free” was given to the extracted casein many years ago

Vitamin mixes

  • The common vitamin mixes shown below use sucrose or corn starch as a carrier
  • Customized vitamin mixes may use cellulose if a non-nutritive carrier is necessary
  • Vitamin mixes are formulated with a diet inclusion rate in mind. Using more or less than recommended could impair the health of your laboratory animal
  • For those preparing their own diets, vitamin premixes are an efficient way to add vitamins to a diet
  • Vitamin mixes should be stored at 4 degrees celsius or lower upon receipt. Storage at –20 degrees celsius is recommended if the mix will be used beyond 1 month
  • Minimum order is 500 g for both stock and custom vitamin mixes
  • Our available vitamin mixes are commonly used in diets, and are available from stock
  • Vitamin mixes are shipped within a few days of order

Our Formula examples

Mineral mixes

  • The common mineral mixes shown below as examples use sucrose as a carrier
  • Customized mineral mixes could use cellulose or no carrier if a non-nutritive carrier is necessary
  • Our mineral mixes are formulated with a diet inclusion rate in mind. Using more or less than recommended could impair the health of the animal
  • For those preparing their own diets, mineral premixes are an efficient way to add minerals to a diet
  • Mineral mixes should be stored in a dry cool environment and used within a year of receipt. The minimum order is 500 g for both stock and custom mineral mixes
  • These mineral mixes are commonly used in diets, and are available from stock
  • Our mineral mixes are shipped within a few days of order

Formula examples:

Other mixes (may or may not be available from stock):

  • TD.83171     Vitamin mix without A, D, E, choline
  • TD.81062     Iron deficient mineral mix based on AIN-76A
  • TD.79055     Calcium and phosphorus deficient mineral mixed based on AIN-76
  • TD.98057     Calcium and phosphorus deficient mineral mixed based on AIN-93
  • CA.170760   Rogers-Harper mineral mix

harlan teklad官网动物饲料代理商 他莫昔芬饮食 Tamoxifen diets TD.130855

harlan teklad官网动物饲料代理商

他莫昔芬饮食 harlan teklad官网动物饲料代理商 他莫昔芬饮食 Tamoxifen diets TD.130855

他莫昔芬激活Creer的饮食

有几篇文献引用了含有他莫昔芬的饮食对CRE模型在雌激素受体突变的控制下的应用。恩维戈特克乐饮食使各种含他莫昔芬的饮食定制,以满足您的研究需要。我们还制作了各种各样的含多西环素饮食对于被监管的系统。如果你有任何问题,请咨询营养师。

枸橼酸他莫昔芬和他莫昔芬

他莫昔芬作为他莫昔芬-蔗糖混合物添加到饮食中.鼓励用户使用库存供应。然而,泰克乐将继续与客户准备的混合。如果您选择此选项,请咨询营养师,以获得有关配制和发送混合物的更多信息。

鼓励用户从以下库存选项中进行选择,以便在几天内随时可供装运。

特克乐提供USP级三苯氧胺和枸橼酸他莫昔芬的饮食。
他莫昔芬
每公斤饲料毫克
日他莫昔芬
每公斤体重毫克1
饮食编码
(特克勒德供应他莫昔芬)
    天然色 红色
250 40 TD.130855 TD.130856
500 80 TD.130857 TD.130858
400柠檬酸盐2 40 TD.130859 TD.1308603

1假设体重20-25克,摄入量3-4克。
2枸橼酸他莫昔芬为66%他莫昔芬
3在欧洲称为TAM 400/Creer(TD.55125)

请为辐照饮食增加5-10天的准备时间;库存和定制产品至少需要3公斤订单。

这些饲料都有他莫昔芬与~5%蔗糖预混合,作为一种适口性增强剂;然而,饲料厌恶仍有可能发生。如果摄入是一个问题,请参阅下面的建议。

TeculadGlobal2016-这些例子中的基础饮食-仅仅是少数几种植物雌激素饮食中的一种。咨询营养学家关于其他基础饮食的使用。

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  • 最低订货量为3公斤,足以喂养20只小鼠一个月。
  • 储存冷冻饮食,并计划在六个月内使用。
  • 典型的准备时间为两周(如果经过辐照,则为四周)
  • 辐照(可选)20 kGy的最低剂量(必须按顺序要求)
  • 订购:请致电800.483.5523或在线启动订单

计划:

  • 最初减少食物摄入量和减肥
  • 日常观察动物的耐受性-咨询您的IACUC监测指标。
  • 必要时进行干预

如果摄入似乎是一个问题:

  • 通过进行他莫昔芬给药试验,确定低剂量对你的模型是否有效。
  • 用含他莫昔芬颗粒与常规饲料颗粒混合逐渐驯服小鼠
  • 把食物弄湿,然后放在笼子里的盘子里(需要每天更换)。
  • 平日喂饲他莫昔芬饮食,周末有规律饮食。
  • 每隔一周(三苯氧胺饮食两周,休息一周)进行更长时间的治疗
  • 他莫昔芬是一种选择性雌激素受体调节剂(SERM),这意味着它可以抑制雌激素的作用或具有促进雌激素的作用。
  • 人体治疗效果的一般剂量为20毫克/天。用于啮齿动物的他莫昔芬饮食通常含有~1至2毫克/粒。
  • 当处理饮食时,可以使用典型的实验室预防措施,如实验室外套、手套和面罩,尽量减少接触他莫昔芬的事故。
  • 您的化学品安全部门应联系,以获得更多的机构特定的指导方针,以处理和处置含有他莫昔芬的饮食。
  • 治疗时间从一周到两周不等。1,2,5,6,7,8一至两个月3,4,8
  • 纯他莫昔芬1,5,8和枸橼酸他莫昔芬1,2,3,4,6,7都是有效的
  • 通常他莫昔芬剂量为每天40-80毫克/公斤体重。
  • 纯他莫昔芬的典型包合物为250 mg。8或500毫克1,5枸橼酸他莫昔芬为每公斤400毫克。1,2,3,4,6,7
  • 报告的初始重量损失为10%。1,2,4,7,8,与食物摄入量减少有关2
  • 恢复正常饮食后体重的恢复可能会因基因失活而受损。2,7
  1. 安德森·KB,Winer LH,Mork HK,Molkentin JD,Jaisser F.2010。他莫昔芬诱导CRE介导的小鼠心脏基因断裂的给药途径和剂量。 转基因RES 19:715-725。
  2. 蒋介明,凌杰,郑永赫,价格DL,Aja SM,Wong PC.2010年。TDP-43的缺失下调了与肥胖相关的基因Tbc1d1,并改变了身体的脂肪代谢。 美国Acad Sci美国:16320-16324。
  3. Kardakaris R.,Gareus R.,Xandomlea S,Pasparakis M.2011。内皮和巨噬细胞特异性P38αMAPK缺乏不影响ApoE-/-小鼠动脉粥样硬化的发病机制。 PLOSOne 6:e21055。
  4. [2]Kiermayer C,Conrad M,Schneider M,Schmidt J,Brielmeier M.枸橼酸他莫昔芬口服对小鼠心脏时空基因灭活的优化。 创世纪45:11-16。
  5. Koitabashi N,Bedja D,Zaiman AL,Pinto Ym,Zhang M,Gabrielson KL,Takimoto E,Kass DA。2009年。心肌细胞靶向他莫昔芬诱导MerCreMer基因缺失模型中短暂性心肌病的避免。 中国保监会第105:12-15号决议
  6. Kratsios P,Catela C,Salimova E,Huth M,Berno V,Rosenthal N,Morkioti F.2009。细胞自主Notch信号在胚胎和成年心脏心肌细胞中的独特作用。 PCirc第106:559-572号决议。
  7. Miro-Murillo M,Elorza A,Soro-ArNaiz I,Albacete-Albacete L,Ordonz A,Balsa E,Vara-Vega A,Vazquez S,Fuertes E,Fernandez-Criado C,Landazuri MO,Aragones J.2011。急性VHL基因失活可诱导心脏HIF依赖的促红细胞生成素基因表达. PLOS One 6:E 22589。
  8. Welle S,Burgess K,Thornton CA,Tawil R.2009。成熟小鼠肌生长抑素耗竭程度与肌肉生长的关系。 李玉玲.医学杂志.1997(4):E 935-40.

Tamoxifen diets

Diets with tamoxifen activate CreER

Several references cite use of tamoxifen-containing diets for models with Cre under the control of a mutated estrogen receptor. Envigo Teklad diets makes a variety of tamoxifen-containing diets customized to meet your research needs. We also make a variety of doxycycline-containing diets for tet regulated systems. If you have any questions, don’t hesitate to consult a nutritionist.

Teklad stocks tamoxifen and tamoxifen citrate

Tamoxifen is added to the diet as a tamoxifen-sucrose mixture. Users are encouraged to use the stocked supply. However, Teklad will continue to work with customer prepared mixes. If you choose this option, please consult a nutritionist for additional information about preparing and sending the mixture.

Users are encouraged to select from the stocked options below supply readily available to ship within days.

Teklad offers diet with USP grade tamoxifen and tamoxifen citrate
Tamoxifen
mg per kg diet
Daily tamoxifen
mg per kg body weight1
Diet code
(Teklad supplied tamoxifen)
    Natural colored Red
250 40 TD.130855 TD.130856
500 80 TD.130857 TD.130858
400 citrate2 40 TD.130859 TD.1308603

1 Assumes 20-25 g body weight and three-four g intake
2 Tamoxifen citrate is 66% tamoxifen
3 Referred to as TAM400/CreER in Europe (TD.55125)

Please add 5-10 day lead time for irradiated diets; minimum 3 kg orders are required for stocked and customized items.

These diets all have tamoxifen premixed with ~five percent sucrose as a palatability enhancer; however, feed aversion may still occur. If intake is a problem, see below for advice.

Teklad Global 2016 — base diet in these examples — is only one of several minimal phytoestrogen diets Teklad produces. Consult a nutritionist about use of other base diets.

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  • Minimum order quantity is three kg, sufficient for feeding ~20 mice for one month
  • Store diet refrigerated and plan to use within six months
  • Typical lead time is two weeks (four weeks if irradiated)
  • Irradiation (optional) minimal dose of 20 kGy (Must be requested at time of order)
  • To place an order: contact Teklad Customer Service at 800.483.5523 or initiate order online

Plan for:

  • Initial reduction in food intake and weight loss
  • Daily observation of animal tolerance — consult your IACUC for monitoring metrics
  • Intervene when necessary

If intake seems to be a problem:

  • Determine if a lower dose is effective for your model by conducting a tamoxifen dose feeding trial
  • Gradually acclimate mice by mixing tamoxifen-containing pellets with regular feed pellets
  • Wet the food, then place in a dish inside the cage (requires daily replacement)
  • Feed tamoxifen diet on weekdays, regular diet on weekends
  • Alternate weeks (two weeks on tamoxifen diet, one week off) for longer treatments
  • Tamoxifen is a selective estrogen receptor modulator (SERM) meaning it can repress actions of estrogen or have pro-estrogen effects
  • Usual dose for therapeutic effects in humans is 20 mg/day. Tamoxifen diets for rodents typically contain ~one to two mg/pellet
  • Accidental tamoxifen exposure can be minimized by using typical lab precautions of lab coat, gloves, and mask when handling the diet.
  • Your chemical safety department should be contacted for additional institution specific guidelines for handling and disposal of tamoxifen containing diets.
  • Length of treatment varies from one to two weeks1,2,5,6,7,8 to one to two months3,4,8
  • Pure tamoxifen1,5,8 and tamoxifen citrate1,2,3,4,6,7 are both effective
  • Usual tamoxifen doses are ~40-80 mg per kg body weight per day
  • Typical inclusion for pure tamoxifen is 250 mg8 or 500 mg1,5 and for tamoxifen citrate is 400 mg per kg diet1,2,3,4,6,7
  • Initial weight loss of ten % is reported1,2,4,7,8, associated with reduced food intake2
  • Subsequent recovery of body weight after returning to regular diet may be compromised by gene inactivation2,7
  1. Andersson KB, Winer LH, Mork HK, Molkentin JD, Jaisser F. 2010. Tamoxifen administration routes and dosage for inducible Cre-mediated gene disruption in mouse hearts. Transgenic Res 19:715-725.
  2. Chiang PM, Ling J, Jeong YH, Price DL, Aja SM, Wong PC. 2010. Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proc Natl Acad Sci USA 107:16320-16324.
  3. Kardakaris R, Gareus R, Xanthoulea S, Pasparakis M. 2011. Endothelial and macrophage-specific deficiency of P38alpha MAPK does not affect the pathogenesis of atherosclerosis in ApoE-/- mice. PLoS One 6:e21055.
  4. Kiermayer C, Conrad M, Schneider M, Schmidt J, Brielmeier M. 2007. Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrate. Genesis 45:11-16.
  5. Koitabashi N, Bedja D, Zaiman AL, Pinto YM, Zhang M, Gabrielson KL, Takimoto E, Kass DA. 2009. Avoidance of transient cardiomyopathy in cardiomyocyte-targeted tamoxifen-induced MerCreMer gene deletion models. Circ Res 105:12-15.
  6. Kratsios P, Catela C, Salimova E, Huth M, Berno V, Rosenthal N, Mourkioti F. 2009. Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart. PCirc Res 106:559-572.
  7. Miro-Murillo M, Elorza A, Soro-Arnaiz I, Albacete-Albacete L, Ordonez A, Balsa E, Vara-Vega A, Vazquez S, Fuertes E, Fernandez-Criado C, Landazuri MO, Aragones J. 2011. Acute Vhl gene inactivation induces cardiac HIF-dependent erythropoietin gene expression. PLoS One 6:e22589.
  8. Welle S, Burgess K, Thornton CA, Tawil R. 2009. Relation between extent of myostatin depletion and muscle growth in mature mice. Am J Physiol Endocrinol Metab.Oct;297(4):E935-40.

Harlan teklad官网动物饲料 异黄酮调节 AIN-76A AIN-93g AIN-93M

异黄酮调节 Isoflavone adjusted

Harlan teklad官网动物饲料 异黄酮调节 AIN-76A,AIN-93g,AIN-93M

异黄酮是一种植物雌激素,存在于大豆蛋白中。大多数传统的标准饮食以豆粕为主要成分,因此是异黄酮的重要来源。请参阅常见问题有关植物雌激素的更多信息。

相比之下,酪蛋白基础的纯化饮食,如AIN-76A,AIN-93g,AIN-93M,以及含有类似成分的配方,基本上不含异黄酮。这种类型的饮食有时被用于研究,需要最低限度的异黄酮背景。这种饮食可以作为异黄酮如染料木黄酮(Genistein)的背景。客户提供的)可以添加。

一种替代纯酪蛋白饮食的方法是我们的全球啮齿动物饮食系列中的天然成分饮食。这一系列中的几种饮食含有极小的异黄酮/植物雌激素水平,并且通常用于需要最小异黄酮/植物雌激素背景的研究。这类饮食也可用作异黄酮如染料木素(Genistein)的背景。客户提供的)可以添加。

Isoflavones, a type of phytoestrogen, are found in soy protein. Most traditional standard diets have soybean meal as a major ingredient, and therefore are a significant source of isoflavones. Please refer to FAQ section for more information about phytoestrogens.

In contrast, casein-based purified diets such as AIN-76A, AIN-93G, AIN-93M, and formulas with similar ingredients, are essentially free of isoflavones. This type of diet is sometimes used for research that requires a minimal isoflavone background. This type of diet can be used as the background to which isoflavones such as genistein (supplied by the customer) can be added.

An alternative to a purified, casein-based diet is a natural ingredient diet from our global rodent diet line. Several diets in this line contain minimal isoflavone/phytoestrogen levels and are commonly used for research that requires a minimal isoflavone/phytoestrogen background. This type of diet can also be used as the background to which isoflavones such as genistein (supplied by the customer) can be added.

Harlan teklad官网动物饲料 Swine diets猪日粮 国内动物饲料定制

Harlan teklad官网动物饲料 Swine diets猪日粮 国内动物饲料定制

特克拉德猪日粮是一种特殊配方的天然饲料,旨在提供对猪的生长、维持和繁殖至关重要的所有已知营养素的适当平衡。

特克勒德猪日粮通过固定配方日粮提供统一的营养,以尽量减少营养差异,否则,如果饲料的成分组成从一批改变到下一批。

由鱼类和植物来源提供的蛋白质,再加上补充氨基酸,提供了研究猪所需必需氨基酸的适当数量和平衡。

特克勒德猪的饮食适当强化维生素和矿物质,以帮助支持调节体液和适当的身体系统的功能,以确保足够的生长,维护和繁殖的研究猪。

特克拉德猪的饮食配方和制造没有人工防腐剂,抗结块剂,或其他添加剂,否则可能影响某些类型的研究结果。

产品
特克勒德猪日粮 不可蒸压式
美酒饮食 7037、7037 C
特克勒德素食猪/母猪种植者饮食 7200
美酒饮食 8753、8753 C
并不是所有的产品都是在当地库存的,可能需要延长交货期和额外的费用。
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。
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没有一个确定的点,人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲,当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月,有时甚至在生产后12个月。这种实践经验,随着时间的推移,再加上文献支持和维生素测试,让我们相信,这些饮食继续支持动物的健康和研究的完整性,至少在9个月后生产。如果你不确定当地的政策,请向你的机构寻求指导。

建议的储存条件:

  • 凉爽和干燥;在华氏70度或以下,湿度最好在50%以下,但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中,防止连续暴露于光线下,并将空气暴露在最小范围内。

应该允许断奶的猪[医]锂节食的机会。成年人应该以每天体重的百分之二到百分之三的速度喂食。新鲜的干净的水应该总是可用的。

Teklad swine diets are natural-ingredient diets specifically formulated to provide the proper balance of all known nutrients considered essential for the growth, maintenance, and reproduction of swine.

Teklad swine diets provide uniform nutrition through fixed-formula diets designed to minimize the nutrient variances that otherwise could occur if the ingredient composition of the diets were altered from one batch to the next.

Protein supplied by fish and plant sources combined with supplemental amino acids provides the proper amount and balance of essential amino acids required by research swine.

Teklad swine diets are fortified appropriately with vitamins and minerals to help support the regulation of body fluids and the proper functioning of the body system to ensure adequate growth, maintenance, and reproduction of research swine.

Teklad swine diets are formulated and manufactured without artificial preservatives, anti-caking agents, or other additives that otherwise may influence the results of certain types of research studies.

Products
Teklad swine diets Non-autoclavable form
Teklad miniswine diet 7037, 7037C
Teklad vegetarian pig/sow grower diet 7200
Teklad miniswine diet 8753, 8753C
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

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There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.

Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit with humidity ideally below 50%, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

Weaning pigs should be allowed ad libitum access to diet. Adults should be fed at a rate of two percent to three percent of their body weight per day. Fresh, clean water should always be available.

harlan teklad官网代理商 标准胆固醇 TD.120097 TD.01383 TD.07841 动物饲料

Standard, natural ingredient diets with cholesterol added are fed to induce hypercholesterolemia. Various levels of cholesterol, fat, and/or bile salts can be added to one of the numerous standard rodent diets stocked by Envigo Teklad. For many applications, adding these components to Envigo’s minimal-to-moderate phytoestrogen global rodent diets is recommended. Our minimal phytoestrogen global rodent diets are soybean meal free, limiting the effect of phytoestrogens on your research outcomes. Soybean meal, a common dietary source of phytoestrogens, has been shown to decrease aortic fatty streak development and modify plasma cholesterol, which may reduce the risk of developing atherosclerosis. Limiting dietary soybean meal may reduce confounding variables within your dietary-induced atherosclerosis model. Contact a nutritionist to discuss additional diet options.

Examples of minimal and moderate phytoestrogen rodent diets with added cholesterol:

  • TD.120097  1% cholesterol diet (2020 – minimal phytoestrogens)
  • TD.07841    2% cholesterol diet (2016 – minimal phytoestrogens)
  • TD.01383    2% cholesterol (2018 – Moderate phytoestrogens)

Research use:

Induce hypercholesterolemia in genetically-modified and wild type models without promoting obesity.

Key dietary features:

  • Standard, grain-based rodent diet
  • Minimal/moderate phytoestrogen diets recommended
  • Cholesterol (1 – 4%)

References:

  1. Belch, J.J., et al., Longitudinal assessment of endothelial function in the microvasculature of mice in-vivo. Microvasc Res, 2013. 85: p. 86-92.
  2. Hartvigsen, K., et al., A diet-induced hypercholesterolemic murine model to study atherogenesis without obesity and metabolic syndrome. Arterioscler Thromb Vasc Biol, 2007. 27(4): p. 878-85.

Rabbits, hamsters, and swine are common models of atherosclerosis. Contact a nutritionist for information and formula examples. See rabbit, swine and other speciesfor information and formula examples.

Harlan teklad官网动物饲料 Primate diets 灵长类饮食 国产动物饲料定制

Harlan teklad官网动物饲料 Primate diets 灵长类饮食 国产动物饲料定制

特克拉德灵长类饮食是固定的配方饮食,以提供适当的营养平衡所需的新世界和旧世界灵长类动物的所有品种和年龄。饮食是为了提供统一的实验和生产结果而制定的。

植物、牛奶和鱼类蛋白质来源的结合提供了必需氨基酸的适当数量和平衡,以维持研究灵长类在其整个生命周期和研究功能中的物理状况。

高质量的脂肪来源提供了生长、维持和繁殖所需的必需脂肪酸的平衡。这些脂肪来源也提供了一种高可消化的能源。

特克拉德灵长类饮食强化维生素和矿物质,包括维生素D 3,以适当的骨发育和维生素C预防坏血病和贫血。稳定维生素C(L-抗坏血酸-2-聚磷酸)用于延长保质期.饮食是营养完整和平衡的,因此额外的饮食补充剂是不必要的。

特克拉德灵长类食物被挤压出来,以帮助分解淀粉,提高消化率和适口性。喂食高可消化的膨化食物会产生坚固的大便,这有助于减少清洗时间。

产品
特克拉德灵长类食物 不可蒸压式
全球20%蛋白质灵长类食物 2050
特克乐全球25%蛋白质灵长类食物 2055
高纤维灵长类食物 7195
15%猴子饮食 8714
15/10高纤维猴子饮食 8788
新世界灵长类食物 8794
并不是所有的产品都是在当地库存的,可能需要延长交货期和额外的费用。
许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。
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没有一个确定的点,人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲,当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月,有时甚至在生产后12个月。这种实践经验,随着时间的推移,再加上文献支持和维生素测试,让我们相信,这些饮食继续支持动物的健康和研究的完整性,至少在9个月后生产。如果你不确定当地的政策,请向你的机构寻求指导。

建议的储存条件:

  • 凉爽和干燥;在华氏70度或以下,湿度最好在50%以下,但高达65%是可以接受的。
  • 清洁无害虫
  • 在原始包装中或容器中,防止连续暴露于光线下,并将空气暴露在最小范围内。

一般来说,非人类灵长类动物将消耗相当于其体重百分之四的食物,但是有许多因素可以影响日常消费,包括物种、生命阶段、住房和环境条件。少量的水果、蔬菜或坚果可以作为环境丰富的食物。清洁的淡水应始终可用。

Teklad primate diets are fixed-formula diets formulated to provide the proper balance of nutrients required by new-world and old-world primates of all breeds and ages. Diets are formulated to provide uniform experimental and production results.

A combination of plant, milk and fish protein sources supplies the proper amounts and balance of essential amino acids necessary to maintain the physical condition of research primates throughout their life cycle and research function.

High-quality fat sources provide the balance of essential fatty acids required for growth, maintenance, and reproduction. These sources of fat also provide a highly digestible source of energy.

Teklad primate diets are fortified with vitamin and minerals including vitamin D3 for proper bone development and vitamin C for prevention of scurvy and anemia. Stabilized vitamin C (L-ascorbyl-2-polyphosphate) is used to extend the shelf life. Diets are nutritionally complete and balanced making additional dietary supplements unnecessary.

Teklad primate Diets are extruded to help break down starches, improving digestibility and palatability. Feeding highly digestible extruded diets results in firm stools, which helps reduce cleaning time.

Products
Teklad primate diets Non-autoclavable form
Teklad global 20% protein primate diet 2050
Teklad global 25% protein primate diet 2055
Teklad hi-fiber primate diet 7195
Teklad 15% monkey diet 8714
Teklad 15/10 hi-fiber monkey diet 8788
Teklad new world primate diet 8794
Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

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There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.

Recommended storage conditions:

  • Cool and dry; at or below 70 degrees fahrenheit with humidity ideally below 50%, but up to 65% is acceptable
  • Clean and free of pests
  • In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air

In general, nonhuman primates will consume an amount of diet equal to four percent of their body weight but there are many factors that can affect daily consumption including species, life-stage, housing, and environmental conditions. Small amounts of fruits, vegetables, or nuts may be fed as environmental enrichment. Clean fresh water should always be available.

harlan teklad官网动物饲料代理商 基础饲料 TD.00235基础配料 TD.88232基础混合

harlan teklad官网动物饲料代理商 基础饲料 TD.00235基础配料 TD.88232基础混合

您可能需要在您自己的设施中添加一些特定的成分。在这种情况下,Envigo提供的基本混合,从设计上来说,是额外包含的起点。当你选择基本的混合饮食时,你只需按你所需的特定比例添加任何成分。在我们的基础组合中的营养水平被调整,以考虑稀释添加的成分(S),以便最终完整的饮食包含所需的营养水平。

  • TD.00235基础配料(93%);无脂肪Aln-93g
  • TD.88232基础混合(不含20%油)

下面是一些基本组合对您有帮助的例子:

  • 将脂肪源的全部或一部分排除在外。最终用户可以添加各种脂肪,并从一个基础混合物中进行多种饮食。
  • 根据需要为不稳定、危险或有限的供应成分制定新鲜饮食。
  • 在相同的基础组合中加入不同的维生素或矿物质混合物,以创造一系列维生素或矿物质调整饮食。

如果有适当的混合设备,并且你有能力喂粉饮食,基础混合提供灵活性和经济性。

You may want to add some specific ingredients in your own facility. In that case, Envigo provides basal mixes that are, by design, a starting point for additional inclusions. When you choose a basal mix diet, you simply add any ingredient(s) in a specific proportion that your require. The nutrient levels in our basal mix are adjusted to account for the dilution of the added ingredient(s), so that the final complete diet contains the desired nutrient levels.

  • TD.00235      Basal mix (93%); AIN-93G without fat
  • TD.88232      Basal mix (without 20% Oil)

Here are some examples of how a basal mix could be helpful to you:

  • Leave all or a portion of the fat source out. The end user can add various fats and make multiple diets from one basal mix
  • Make fresh diet as needed for an unstable, hazardous, or limited supply ingredient
  • Add a different vitamin or mineral mix to the same basal mix to create a series of vitamin or mineral adjusted diets

If proper mixing equipment is available, and you have the capability to feed powder diet, basal mixes offer flexibility and economy.

harlan teklad官网动物饲料 兔子 猪 几内亚猪 仓鼠、沙土鼠 TD.92033猪日粮

The most common custom rabbit diets are those with a standard diet base and added cholesterol. Typically, the added cholesterol ranges from 0.25% to two percent. Additional fat can also be a feature of these formulas. To preserve pellet quality we recommend no more than six percent additional fat. Added fat is most often supplied as peanut oil, corn oil, coconut oil, or a combination. We recommend the Teklad base diets 2030 or 2031.

Rabbits do not readily consume purified diet. When specific nutrient manipulations are necessary, hybrid diets or at least some alfalfa meal inclusion is recommended. Contact us for formula examples or to discuss your specific needs.

Most often, customized diets for swine feature natural ingredients with added fat and cholesterol. Here are three variations on this theme:

  • TD.92033      Swine diet (15% lard, 1.2% cholesterol)
  • TD.92052      Swine diet (15% lard, 1.5% cholesterol)
  • TD.93296      Swine diet (15% lard, two perecent cholesterol)

We recommend these diets in meal/powder form, as pellets are not very durable. Other natural ingredient and purified diets with various nutrient manipulations are available. Contact us for further information.

The most common custom Guinea pig diets are those with a standard diet base (such as Teklad 2040 or 2041) and added cholesterol.

Guinea pigs do not readily consume purified diets, so when specific nutrient manipulations are necessary, hybrid diets (mixture of refined and natural ingredients) are recommended. At the very least it is advisable to retain some alfalfa meal in the diet. Contact us for further information.

Most times, diets that are developed for mice and rats are suitable for hamsters and gerbils, and vice versa. We may advise increasing specific nutrients in a purified diet for hamsters and gerbils. Contact us for further information.

Depending on the focus of your research, customized diet for non-human primates can contain natural ingredients, refined ingredients, or a mixture of both.  Custom diets for primates often feature adjustments in fat type, fat level, and cholesterol. Contact us for further information.