荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP]
![荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP] 货号13606](http://www.jinpanbio.com.cn/wp-content/uploads/2022/09/20220925_632faf2f8d9ff.svg) |
货号 |
13606 |
存储条件 |
在零下15度以下保存, 避免光照 |
| 规格 |
100 nmol |
价格 |
6564 |
| Ex (nm) |
552 |
Em (nm) |
578 |
| 分子量 |
1309.30 |
溶剂 |
DMSO |
| 产品详细介绍 |
简要概述
产品基本信息
货号：13606
产品名称：荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP]
规格：100 nmol
储存条件：-15℃避光防潮
保质期：24个月
产品物理化学光谱特性
分子量：1309.30
溶剂：DMSO
激发波长(nm)：544
发射波长(nm)：575
产品介绍
荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP]是美国AAT Bioquest生产的荧光底物，荧光标记的ADP分子用于筛选ADP结合酶和其他蛋白质靶标用于药物发现。 该ADP-TAMRA已经测试了K（d）值为0.60±0.05？M的结合犬尿氨酸单加氧酶（KMO）和来自烟曲霉和耻垢分枝杆菌的NMO，K（d）值为2.1±0.2和4.0± 分别为0.2 M（Anal Biochem。2012,425,80-7）。 在与KMO和NMO的底物和产物的竞争性结合实验中测试该测定。 NMO对于真菌和细菌的发病机制至关重要。 NMO在含异羟肟酸的铁载体的生物合成中催化正弦和鸟氨酸的羟基化。 抑制KMO，催化犬尿氨酸转化为3-羟基犬尿氨酸，缓解神经退行性疾病，如亨廷顿氏症和阿尔茨海默氏症以及寄生虫布氏锥虫引起的脑部感染。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP]。
点击查看光谱
参考文献
Deciphering the catalysis-associated conformational changes of human adenylate kinase 1 with single-molecule spectroscopy
Authors: Lin CY, Huang JY, Lo LW.
Journal: J Phys Chem B (2013): 13947
The effect of NBD-Cl in nucleotide-binding of the major subunit alpha and B of the motor proteins F1FO ATP synthase and A1AO ATP synthase
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Journal: J Bioenerg Biomembr (2010): 1
The Escherichia coli PriA helicase-double-stranded DNA complex: location of the strong DNA-binding subsite on the helicase domain of the protein and the affinity control by the two nucleotide-binding sites of the enzyme
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Journal: J Mol Biol (2010): 344
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Reversal of ADP-mediated aggregation of adenosine kinase by cyclophilin leads to its reactivation
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Journal: Biochemistry (2006): 263
ATPase mechanism of Eg5 in the absence of microtubules: insight into microtubule activation and allosteric inhibition by monastrol
Authors: Cochran JC, Gilbert SP.
Journal: Biochemistry (2005): 16633
Ca2+ binding to sarcoplasmic reticulum ATPase phosphorylated by Pi reveals four thapsigargin-sensitive Ca2+ sites in the presence of ADP
Authors: Vieyra A, Mintz E, Lowe J, Guillain F.
Journal: Biochim Biophys Acta (2004): 103
Evidence for proximal cysteine and lysine residues at or near the active site of arginine kinase of Stichopus japonicus
Authors: Guo Q, Chen B, Wang X.
Journal: Biochemistry (Mosc) (2004): 1336
Conformational dynamics of DnaB helicase upon DNA and nucleotide binding: analysis by intrinsic tryptophan fluorescence quenching
Authors: Flowers S, Biswas EE, Biswas SB.
Journal: Biochemistry (2003): 1910
D1 ring is stable and nucleotide-independent, whereas D2 ring undergoes major conformational changes during the ATPase cycle of p97-VCP
Authors: Wang Q, Song C, Yang X, Li CC.
Journal: J Biol Chem (2003): 32784
说明书
荧光标记的ADP-TAMRA conjugate [5-TAMRA-eda-ADP].pdf
